Aggregation-Induced Generation of Reactive Oxygen Species: Mechanism and Photosensitizer Construction
Juechen Ni1, Yijia Wang2, Haoke Zhang1
1MOE Key Laboratory of Macromolecular Synthesis and Functionalization, Department of Polymer Science and Engineering, Zhejiang University, Hangzhou 310027, China.
Abstract:
Luminogens with aggregation-induced emission (AIEgens) have been widely applied in the field of photodynamic therapy. Among them, aggregation-induced emission photosensitizers (AIE-PSs) are demonstrated with high capability in fluorescence and photoacoustic bimodal imaging, as well as in fluorescence imaging-guided photodynamic therapy. They not only improve diagnosis accuracy but also provide an efficient theranostic platform to accelerate preclinical translation as well. In this short review, we divide AIE-PSs into three categories. Through the analysis of such classification and construction methods, it will be helpful for scientists to further develop various types of AIE-PSs with superior performance.
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