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Reactive Oxygen Species, Aging, and Antioxidative Nutraceuticals
1Author Lee is currently with the Dept. of Food Science and Technology, Seoul National Univ. of Technology, Seoul, Korea.
Comprehensive Reviews in Food Science and Food Safety
|January 12, 2021
Summary
Reactive oxygen species contribute to aging diseases. Antioxidative nutraceuticals from diet combat these effects, preventing age-related illnesses and promoting healthy aging.
Area of Science:
- Biochemistry
- Gerontology
- Nutritional Science
Background:
- Reactive oxygen species (ROS) are byproducts of aerobic metabolism.
- ROS can damage lipids, proteins, and DNA, contributing to age-related diseases.
- The body possesses endogenous antioxidant defenses, but these can be overwhelmed.
Purpose of the Study:
- To review the role of ROS in aging and associated diseases.
- To highlight the importance of antioxidative nutraceuticals in disease prevention and healthy aging.
- To discuss the scientific and consumer trends in antioxidative nutraceuticals.
Main Methods:
- Literature review of recent scientific reports and epidemiological studies.
- Analysis of the biochemical mechanisms of ROS generation and damage.
- Examination of the role of dietary antioxidants and nutraceuticals.
Main Results:
- ROS are implicated in numerous age-related diseases, including atherosclerosis, cancer, and arthritis.
- Antioxidant nutraceuticals can neutralize ROS or support endogenous antioxidant enzymes.
- Epidemiological data supports the link between antioxidative nutraceuticals and reduced risk of age-related diseases.
Conclusions:
- Antioxidative nutraceuticals are crucial for preventing oxidative stress-related diseases.
- These compounds play a vital role in promoting healthy aging.
- The growing consumer interest reflects the recognized health benefits of antioxidative nutraceuticals.
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