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Metabolite profiling of Cyanthillium cinereum (L.) H. Rob. and its herbal formulation by tandem mass spectroscopic
C T Sulaiman1, P R Ramesh2, K Mahesh2
1Centre for Medicinal Plants Research, Kottakkal, Kerala, India.
Abstract:
Cyanthillium cinereum is a medicinal plant commonly known as little ironweed is used in various traditional systems of medicines. In Ayurveda, it is known as Sahadevi and is used as remedy for many ailments. It has been reported to possess numerous biological properties including diaphoretic, anthelmintic, diuretic, lithontriptic, anti-inflammatory and anticancer activities. Metabolite profiling of aqueous extract of C. cinereum (CCE) and its herbal formulation KGS tablet has been carried out by liquid chromatography tandem mass spectroscopic analysis. ESI-MS/MS based characterisation led to the identification of several bioactive phytochemicals belonging to various classes of metabolites like phenolic acids, phenolic glycosides, flavonoids and anthocyanin. Most of the identified compounds are known for their various biological properties, such as antioxidant, anti-inflammatory and anticancer activities.
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