Related Experiment Video

Updated: Nov 21, 2025

Assessing Murine Resistance Artery Function Using Pressure Myography
07:25

Assessing Murine Resistance Artery Function Using Pressure Myography

Published on: June 7, 2013

22.7K

Factors Associated with Primary Hypertension in Pediatric Patients: An Up-to-Date

Isabella Barreto S Machado1, Matheus Rampinelli Tofanelli1, Ariadna A Saldanha da Silva1

  • 1Interdisciplinary Laboratory of Medical Investigation, Faculty of Medicine, Federal University of Minas Gerais (UFMG), Belo Horizonte, MG, Brazil.

Current Pediatric Reviews
|January 12, 2021
PubMed

Insights

Childhood arterial hypertension is multifactorial, influenced by genetics and environment. Understanding these factors is crucial for prevention and treatment of pediatric hypertension.

Area of Science:

  • Pediatric Cardiology
  • Public Health
  • Genetics

Background:

  • Childhood arterial hypertension is increasingly common, linked to rising global obesity rates.
  • Primary hypertension in children lacks fully understood pathophysiology, with ongoing debate on underlying mechanisms.
  • Key factors include genetics, diet (sodium/potassium), socioeconomic status, ethnicity, lifestyle, and birth conditions.

Purpose of the Study:

  • To update knowledge on primary hypertension in childhood.
  • To provide an overview of genetic and environmental factors influencing pediatric hypertension.
  • To inform clinicians and researchers on the current literature.

Main Methods:

  • Integrative review of scientific articles.
  • Searched databases: PubMed and Scopus.
  • Focused on genetic and environmental factors in pediatric primary hypertension.

Main Results:

  • Identified numerous genetic and environmental factors associated with pediatric primary hypertension.
  • Confirmed primary hypertension as a multifactorial disease in children.
  • Highlighted the need for further research to clarify underlying mechanisms.

Conclusions:

  • Studying pediatric primary hypertension is vital for developing preventive strategies.
  • Enhanced understanding can lead to more effective treatments for childhood hypertension.
  • Early intervention reduces long-term cardiovascular disease and morbidity.
Abstract

Keywords:
Primary hypertensionarterial hypertensionblood pressurecardiovascular diseasesenvironmental factorsgenetic factorspediatricsrisk factors

More Related Videos

Author Spotlight: Exploring Huotan Jiedu Tongluo Decoction as an Antihypertensive Drug05:57

Author Spotlight: Exploring Huotan Jiedu Tongluo Decoction as an Antihypertensive Drug

Published on: May 17, 2024

973
Estimation of Nephron Number in Whole Kidney using the Acid Maceration Method08:15

Estimation of Nephron Number in Whole Kidney using the Acid Maceration Method

Published on: May 22, 2019

10.4K

Related Concept Videos

Hypertension I: Introduction01:28

Hypertension I: Introduction

Hypertension is a widespread, long-term medical condition where blood pressure in the arteries remains elevated. It is characterized by systolic blood pressure readings of 130 mm Hg or above or diastolic blood pressure (DBP) readings of 80 mm Hg or higher. Unmanaged hypertension poses significant health risks, making the distinction between primary (or essential) hypertension and secondary hypertension crucial, as their management and implications vary.Primary HypertensionPrimary hypertension,...
343
Factors affecting Blood pressure01:28

Factors affecting Blood pressure

Several physiological and lifestyle factors influence blood pressure (BP). Understanding these factors is crucial as they are significant in patient education and blood pressure management.
Physiological Factors:
5.8K
Hypertension and Regulation of Blood Pressure01:18

Hypertension and Regulation of Blood Pressure

Hypertension, the most common cardiovascular disease, is diagnosed through repeated measurements of elevated blood pressure. Its risks, including damage to the kidney, heart, and brain, are directly proportional to blood pressure levels. Starting from 115/75 mm Hg, the risk of cardiovascular disease doubles with each increment of 20/10 mm Hg. The diagnosis relies on blood pressure measurements, not on patient symptoms, as hypertension is often asymptomatic until end-organ damage is imminent or...
3.5K
Hypertension II: Pathophysiology01:29

Hypertension II: Pathophysiology

Hypertension is a chronic condition in which the blood's force against artery walls is excessively high, posing risks such as heart disease. The condition's underlying mechanisms involve complex interactions among the cardiovascular, kidney, and autonomic nervous systems.Renin-Angiotensin-Aldosterone System (RAAS): This system significantly influences blood pressure regulation. When blood pressure decreases, the kidneys secrete renin. This enzyme transforms angiotensinogen, a plasma protein,...
356
Hypertension III: Clinical Manifestations and Diagnostic Studies01:30

Hypertension III: Clinical Manifestations and Diagnostic Studies

Hypertension is asymptomatic and also referred to as the "silent killer" until it progresses to a severe stage or causes target organ disease. Patients may experience symptoms stemming from the strain on blood vessels and tissues in various organs or the heart's increased workload.Physical exams might show no abnormalities other than high blood pressure. Signs of vascular damage, when present, correspond to the organs supplied by the affected vessels, leading to target organ damage. For...
212
Pharmacokinetics in Pediatric Patients: Drug Distribution01:17

Pharmacokinetics in Pediatric Patients: Drug Distribution

Drug distribution in the pediatric population exhibits unique challenges and considerations due to the physiological differences between children, particularly neonates and infants, and adults. A crucial aspect of pediatric pharmacology is understanding how these differences impact the pharmacokinetics of various drugs, necessitating age-specific dosing strategies to ensure efficacy and safety.Neonates and infants have a higher total body water content, ~75%–90% of their body weight,...
131