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Updated: Nov 21, 2025

Expression and Purification of Virus-like Particles for Vaccination
Published on: June 2, 2016
Vaccinology in the post-COVID-19 era
Rino Rappuoli1, Ennio De Gregorio2, Giuseppe Del Giudice2
1Research and Development Centre, GlaxoSmithKline (GSK), 53100 Siena, Italy; rino.r.rappuoli@gsk.com.
Abstract:
The COVID-19 pandemic is a shocking reminder of how our world would look in the absence of vaccination. Fortunately, new technologies, the pace of understanding new and existing pathogens, and the increased knowledge of the immune system allow us today to develop vaccines at an unprecedented speed. Some of the vaccine technologies that are fast-tracked by the urgency of COVID-19 may also be the answer for other health priorities, such as antimicrobial resistance, chronic infections, and cancer, that the post-COVID-19 world will urgently need to face. This perspective analyzes the way COVID-19 is transforming vaccinology and the opportunities for vaccines to have an increasingly important role in health and well-being.
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