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Long term outcome of heart failure patients disqualified from heart transplantation

Paula Polaska1, Grazyna Jerzak-Wodzynska1, Witold Smigielski2

  • 1Heart Failure and Transplantology Department, Cardinal Stefan Wyszynski National Institute of Cardiology, Warsaw, Poland.

Acta Cardiologica
|January 12, 2021
PubMed

Insights

Patients disqualified from heart transplantation face poor survival, with a 5-year survival rate of 25%. However, specialist care and beta-blocker use improve outcomes for advanced heart failure patients.

Area of Science:

  • Cardiology
  • Transplantation Medicine
  • Clinical Prognostics

Background:

  • Advanced heart failure patients have a poor prognosis.
  • Survival data for patients disqualified from heart transplantation is limited.
  • Understanding prognosis in this group is crucial for patient management.

Purpose of the Study:

  • To evaluate the long-term prognosis of patients disqualified from heart transplantation.
  • To identify factors influencing survival in patients ineligible for heart transplantation.

Main Methods:

  • Retrospective study utilizing medical records.
  • Inclusion of 151 patients disqualified from heart transplantation.
  • Long-term follow-up ranging from 0.02 to 10.1 years.

Main Results:

  • A 5-year survival rate of 25% was observed.
  • Supervision by specialist cardiology centers and beta-blocker pharmacotherapy positively impacted prognosis.
  • Renal failure, pulmonary hypertension, and liver failure were identified as negative predictors of outcome.

Conclusions:

  • Patients disqualified from heart transplantation have an unfavorable prognosis.
  • Certain factors, such as specialist care and specific pharmacotherapy, can improve survival.
  • Careful clinical assessment is vital for optimizing patient selection for heart transplantation.
Abstract

Keywords:
Epidemiologyheart failureheart transplantationprognosissurvival

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