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Identifying Coronary Artery Calcification on Non-gated Computed Tomography Scans
Published on: August 28, 2018
The potential impact of mammographic breast arterial calcification on physician practices in a primary care setting
Melissa Gennarelli1, Andrzej Jedynak2, Leanne Forman1
1Department of Medicine, Division of General Internal Medicine, Westchester Medical Center & New York Medical College, Valhalla, NY 10595, USA.
Insights
Breast arterial calcification (BAC), identified via mammography, is prevalent in primary care. This finding can help identify women who may benefit from additional cardiovascular evaluation, even with low traditional risk scores.
Area of Science:
- Radiology
- Cardiology
- Primary Care Medicine
Background:
- Breast arterial calcification (BAC) is a common finding on mammograms.
- The clinical significance of BAC in primary care settings requires further investigation.
- Assessing BAC may offer insights into cardiovascular risk beyond traditional metrics.
Purpose of the Study:
- To determine the prevalence of breast arterial calcification (BAC) in a primary care population.
- To evaluate the potential of BAC as a marker for guiding cardiovascular workup.
- To compare characteristics of women with and without BAC.
Main Methods:
- Retrospective review of 282 consecutive mammograms by a radiologist.
- Comparison of demographic and clinical characteristics between BAC-positive and BAC-negative women.
- Statistical analysis to assess the association between BAC and cardiovascular risk factors.
Main Results:
- BAC was identified in 34% of women.
- BAC-positive women were older and had higher 10-year cardiac risk, hypertension, and coronary artery disease.
- BAC-positive women also showed increased use of statins and aspirin.
- Approximately 37% of BAC-positive women were identified as potential candidates for further cardiac testing.
Conclusions:
- Mammography can detect BAC, a marker associated with increased cardiovascular risk.
- BAC may help identify individuals with low traditional cardiovascular risk who could benefit from further cardiac evaluation.
- Integrating BAC assessment into routine mammography could enhance cardiovascular risk stratification in primary care.
Abstract:
Aim: This study sought to determine breast arterial calcification (BAC) prevalence in a primary care setting and its potential use in guiding further cardiovascular workup. Materials & methods: A radiologist reviewed 282 consecutive mammograms. Characteristics of BAC-positive and negative women were compared. Results: BAC prevalence was 34%. BAC-positive women were older (mean age: 60 vs 52, p < 0.001), had higher mean 10-year cardiac risk (11 vs 6%, p < 0.001), more hypertension (65 vs 40%, p < 0.001) and coronary artery disease (10 vs 2%, p = 0.0041), statin (50 vs 32%, p = 0.006) and aspirin use (28 vs 16%, p = 0.012). Thirty-seven percent (33/96) of BAC-positive women could potentially benefit from further cardiac testing. Conclusion: Mammography identifies BAC-positive women with low traditionally assessed cardiovascular risk who might benefit from further cardiovascular workup.
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