[Personalized treatment concepts for arterial hypertension]
Related Experiment Video
Updated: Nov 21, 2025

Improved Home Blood Pressure Control by CT-guided Ozone-mediated Renal Denervation for Patients with Resistant Hypertension
Published on: June 6, 2025
Katharina Lechner1,2, Heribert Schunkert3,4
1Klinik für Herz- und Kreislauferkrankungen, Deutsches Herzzentrum München, Technische Universität München, Lazarettstraße 36, 80636, München, Deutschland.
Insights
Arterial hypertension, a major cardiovascular risk, requires personalized management. Recent developments focus on improving diagnosis and tailored treatments, though blood pressure control remains a challenge for many patients.
Area of Science:
- Cardiology
- Internal Medicine
- Public Health
Background:
- Arterial hypertension is the primary risk factor for cardiovascular diseases.
- Diagnosis typically relies on office resting blood pressure, with ambulatory (ABPM) and home (HBPM) monitoring as alternatives.
- Despite guidelines, effective blood pressure control is often inadequate.
Purpose of the Study:
- To provide a perspective on recent developments in arterial hypertension management.
- To highlight the importance of personalized treatment approaches.
- To emphasize the ongoing need for improved diagnostics and therapies.
Main Methods:
- Review of current diagnostic criteria for arterial hypertension.
- Discussion of nonpharmacological and pharmacological management strategies.
- Emphasis on shared decision-making and individualized treatment plans based on comorbidities.
Main Results:
- Arterial hypertension diagnosis involves specific systolic and diastolic pressure thresholds.
- Management strategies include lifestyle modifications and pharmacotherapy.
- Personalized treatment targets are crucial and vary by patient age and comorbidities.
Conclusions:
- Continuous improvement in hypertension perception, diagnostics, and treatment is essential.
- Tailored, personalized approaches are key to optimizing patient outcomes.
- Addressing the persistent challenge of inadequate blood pressure control remains a global healthcare priority.
Abstract:
Arterial hypertension is the most important risk factor for cardiovascular diseases. Arterial hypertension is diagnosed when reproducible office resting blood pressure values are 140 mm Hg or more systolic and/or 90 mm Hg or more diastolic. A recent alternative is to base the diagnosis of hypertension on ambulatory 24 h blood pressure monitoring (ABPM) and/or home blood pressure monitoring (HBPM) if feasible. Nonpharmacological and pharmacological strategies of blood pressure management are available. Treatment decisions should involve a shared decision-making process and pharmacological agents as well as lifestyle recommendations should be tailored to the needs and comorbidities of each individual patient in a personalized approach. The target values depend on age and comorbidities. Despite clear recommendations as depicted in pertinent guidelines, blood pressure control remains inadequate in the majority of hypertensive patients. The continuous improvement of perception, diagnostics and treatment thus remain high priorities in healthcare systems worldwide. The aim of this CME article is to provide a perspective on recent developments in the management of arterial hypertension.
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