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Updated: Nov 21, 2025

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Fertility Preservation in Patients with Severe Ovarian Dysfunction
Published on: March 25, 2021
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[Fertility preservation for transwomen]
E Benaloun1, N Sermondade2, E Moreau1
1Service de biologie de la reproduction CECOS, AP-HP, hôpital Tenon, Paris, France.
Gynecologie, Obstetrique, Fertilite & Senologie
|January 12, 2021
Summary
Fertility preservation for transgender women should be discussed before medical transition to safeguard reproductive options. While access is improving, barriers remain for this crucial aspect of transgender healthcare.
Area of Science:
- Reproductive Medicine
- Endocrinology
- Transgender Healthcare
Background:
- Fertility preservation is increasingly relevant for transgender individuals.
- The reproductive desires of transgender people have historically been overlooked.
- Early discussion of fertility preservation is vital before medical transition.
Purpose of the Study:
- To review the existing literature on fertility preservation for transgender women (male to female).
- To assess the current state of knowledge regarding hormonal treatments' impact on reproductive function.
- To identify improvements and persistent barriers in accessing fertility preservation procedures.
Main Methods:
- Systematic literature review of studies on fertility preservation in transgender women.
- Analysis of research concerning hormonal therapies and their effects on reproductive capacity.
- Examination of factors influencing access to fertility preservation services.
Main Results:
- Growing body of literature indicates improved access to fertility preservation for transgender women.
- Significant uncertainties persist regarding the impact and reversibility of hormonal treatments on reproductive functions.
- Barriers continue to hinder or postpone the initiation of fertility preservation for many individuals.
Conclusions:
- Fertility preservation is a critical component of comprehensive transgender care.
- Further research is needed to clarify the long-term effects of medical transition on fertility.
- Addressing existing barriers is essential to ensure equitable access to reproductive options for transgender women.
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