Management of Descending Thoracic Aortic Diseases: Similarities and Differences Among Cardiovascular Guidelines

Konstantinos Spanos1,2, Petroula Nana1, Christian-Alexander Behrendt2

  • 1Department of Vascular Surgery, Faculty of Medicine, School of Health Sciences, University of Thessaly, Larissa, Greece.

Insights

Cardiovascular guidelines show agreement on managing thoracic aortic diseases, with thoracic endovascular aortic repair (TEVAR) often preferred for dissections and aneurysms. Further evidence is needed for complex pathologies.

Area of Science:

  • Cardiovascular Medicine
  • Thoracic Aortic Diseases
  • Medical Guidelines

Background:

  • Cardiovascular societies provide recommendations for managing thoracic aortic diseases.
  • The increasing use of thoracic endovascular aortic repair (TEVAR) necessitates a review of its indications and limitations.
  • Existing guidelines require assessment for consistency and areas needing further research.

Purpose of the Study:

  • To systematically review and compare current cardiovascular society guidelines for thoracic aortic disease management.
  • To identify similarities, differences, and controversial aspects in guideline recommendations.
  • To highlight areas requiring further investigation and evidence generation.

Main Methods:

  • Systematic review of guidelines from major cardiovascular societies.
  • Searched MEDLINE, EMBASE, and Cochrane Central Register of Controlled Trials (January 2009 - May 2020).
  • Analyzed 5 selected guidelines (2010-2020) focusing on diagnosis, imaging, prevention, and management of various thoracic aortic pathologies.

Main Results:

  • Significant overlap and agreement were found among the 5 reviewed guidelines.
  • Thoracic endovascular aortic repair (TEVAR) is consistently recommended as a primary treatment for aortic dissection and aneurysm.
  • Areas of controversy and 'gray zones' requiring further investigation were identified across different pathologies.

Conclusions:

  • Current guidelines demonstrate substantial consensus on managing thoracic aortic diseases, particularly regarding TEVAR.
  • Despite agreement, robust evidence is still lacking for several thoracic aortic pathologies and specific management strategies.
  • Further research is crucial to address evidence gaps and refine future clinical recommendations.

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