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Related Experiment Videos

Nephroureterectomy after radical cystectomy.

G R Mufti1, J R Gove, P R Riddle

  • 1St. Peter's Hospitals, London, England.

The Journal of Urology
|March 1, 1988
PubMed
Summary

Upper tract urothelial carcinoma can develop after cystectomy with ileal conduit diversion. For treatment with nephroureterectomy, surgeons should excise the ureteroileal anastomosis to prevent recurrence.

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Area of Science:

  • Urology
  • Oncology

Background:

  • Transitional cell carcinoma (TCC) is a common malignancy of the urinary tract.
  • Ileal loop diversion is a surgical procedure used for urinary reconstruction after cystectomy.

Observation:

  • Six cases of upper tract TCC were identified in patients who previously underwent total cystectomy with ileal loop diversion.
  • These secondary TCCs developed in the upper urinary tract, specifically involving the ureters or renal pelvis.

Findings:

  • The study highlights a potential long-term risk of upper tract urothelial carcinoma following cystectomy and ileal conduit urinary diversion.
  • The ureteroileal anastomoses were identified as a critical site for monitoring and potential intervention.

Implications:

  • Nephroureterectomy is a treatment option for upper tract TCC.
  • Excision of the ureteroileal anastomoses during nephroureterectomy is recommended to ensure complete tumor removal and prevent recurrence at this site.

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