Liquid biopsy in cancer using the Z-scan technique: a new approach to discover biomarkers in cancer
Related Experiment Video
Updated: Nov 21, 2025
Detection of Cell-Free DNA in Blood Plasma Samples of Cancer Patients
Published on: September 9, 2020
Fernando Luiz Affonso Fonseca1,2, Glaucia Luciano da Veiga1, Beatriz da Costa Aguiar Alves1
1Clinical Analysis Laboratory, Centro Universitário Saúde ABC, Santo André 06090-650, Brazil.
Aim:
Biomarkers have been broadly studied as a tool for the diagnosis and prognosis for different types of cancer. Z-scan is a kind of measurement technique that generates a nonlinear refractive index (n2). Today, Z-scan has been used in oncology to discriminate between solid tumors and to identify tumor circulating cell-free DNA in liquid samples.
Materials & Methods:
According to the inclusion and exclusion criteria defined in this review, 35 articles were selected.
Conclusion:
The use of this technique for this kind of measurement will allow for a rapid and precise diagnosis of different types of tumor and may lead to better therapeutic approaches.
