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Mutation, Gene Flow, and Genetic Drift

Mutation, Gene Flow, and Genetic Drift

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Related Experiment Video

Updated: Nov 21, 2025

Following the Dynamics of Structural Variants in Experimentally Evolved Populations

Following the Dynamics of Structural Variants in Experimentally Evolved Populations

Published on: February 3, 2023

Markers for genetic change.

Giovanni Forcina^1,2, Miguel Camacho-Sanchez^1,2, Fred Y Y Tuh³

¹Conservation and Evolutionary Genetics Group, Estación Biológica de Doñana (EBD-CSIC), 41092 Seville, Spain.

|January 13, 2021

Summary

This study demonstrates a new method for monitoring wildlife genetic diversity using high-throughput sequencing. This approach effectively captures genetic variability across diverse mammal species for conservation efforts.

Keywords:

Agricultural science Biological sciences Conservation Earth sciences Environmental science Genetics High-throughput sequencing NGS Intron Multiplex Veterinary medicine Wildlife management

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Last Updated: Nov 21, 2025

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An Allele-specific Gene Expression Assay to Test the Functional Basis of Genetic Associations

An Allele-specific Gene Expression Assay to Test the Functional Basis of Genetic Associations

Published on: November 3, 2010

Area of Science:

Ecology
Genetics
Conservation Biology

Background:

Wildlife conservation traditionally focuses on species, but genetic diversity is increasingly recognized as crucial for biodiversity.
Integrating genetic diversity into wildlife monitoring and management remains a challenge.

Purpose of the Study:

To assess the viability of multiplexed, high-throughput sequenced introns for large-scale genetic variability monitoring in diverse small mammal communities.
To outline a bioinformatic pipeline for primer design to enhance applicability across different systems.

Main Methods:

Tested multiplexed intron sequencing in small mammal communities at two UNESCO World Heritage Sites.
Utilized a bioinformatic pipeline for primer design applicable to various species.

Main Results:

Variable genetic loci were identified across multiple mammal orders, though amplification success decreased with increasing phylogenetic distance from reference taxa.
The method proved effective for assessing genetic variability in a broad spectrum of species.

Conclusions:

The genetic variability data are valuable for population genetic, phylogeographic, and phylogenetic analyses.
This approach provides a scalable tool for incorporating genetic diversity into wildlife conservation strategies.