Related Experiment Video

Updated: Nov 21, 2025

A Protocol to Set Up Needle-Free Connector with Positive Displacement on Central Venous Catheter in Intensive Care Unit
09:57

A Protocol to Set Up Needle-Free Connector with Positive Displacement on Central Venous Catheter in Intensive Care Unit

Published on: July 13, 2019

13.4K

Comparing catheter related bloodstream infection rate between cuffed tunnelled and non-cuffed tunnelled peripherally

Teoh Sze Yong1, Anushya A/P Vijayanathan1, Eric Chung1

  • 1Department of Biomedical Imaging, Faculty of Medicine, University of Malaya, Kuala Lumpur, Malaysia.

The Journal of Vascular Access
|January 13, 2021
PubMed

Insights

Tunnelled non-cuffed PICCs are as effective as cuffed PICCs in preventing catheter-related bloodstream infections (CRBSI). Non-cuffed PICCs also offer longer dwell times, making them a potentially superior choice for patients requiring long-term venous access.

Area of Science:

  • Medical Devices
  • Infectious Diseases
  • Vascular Access

Background:

  • Catheter-related bloodstream infections (CRBSI) are a significant complication of central venous catheters.
  • Peripherally inserted central catheters (PICCs) are widely used for long-term venous access.
  • The role of cuffing in tunnelled PICCs for infection prevention is debated.

Purpose of the Study:

  • To compare the CRBSI rate between cuffed tunnelled PICCs and non-cuffed tunnelled PICCs.
  • To evaluate the efficacy of different PICC types in preventing infections.
  • To assess the impact of cuffing on catheter dwell time.

Main Methods:

  • A prospective study involving 100 patients, with 50 receiving cuffed tunnelled PICCs and 50 receiving non-cuffed tunnelled PICCs.
  • Patients were followed until PICC removal due to complications, completion of therapy, death, or study end.
  • CRBSI was confirmed by matching blood culture and catheter tip isolates.

Main Results:

  • The CRBSI rate was 2.7 per 1000 catheter-days for cuffed PICCs (10% of patients) and 1.5 per 1000 catheter-days for non-cuffed PICCs (6% of patients).
  • The mean time to infection was 24 days for cuffed PICCs and 19 days for non-cuffed PICCs.
  • Non-cuffed PICCs had a significantly longer mean duration of utilization (43 days) compared to cuffed PICCs (37 days).

Conclusions:

  • Cuffed tunnelled PICCs do not offer additional protection against local or bloodstream infections compared to non-cuffed tunnelled PICCs.
  • Tunnelled non-cuffed PICCs demonstrate comparable or superior effectiveness in reducing CRBSI risk.
  • Non-cuffed tunnelled PICCs provide a longer catheter dwell time, potentially improving patient care and reducing the need for replacement.
Abstract

Keywords:
Cuffed versus non-cuffedperipherally inserted central catheterstunnelled PICC

More Related Videos

An In Vitro Bladder Model of Catheter-Associated Urinary Tract Infection07:57

An In Vitro Bladder Model of Catheter-Associated Urinary Tract Infection

Published on: June 24, 2025

758
Author Spotlight: Hickman Catheter Use for Long-Term Vascular Access in a Preclinical Swine Model08:51

Author Spotlight: Hickman Catheter Use for Long-Term Vascular Access in a Preclinical Swine Model

Published on: March 31, 2023

4.8K

Related Concept Videos

Parentral Nutrition: Centeral and Peripheral Parental Nutrition01:27

Parentral Nutrition: Centeral and Peripheral Parental Nutrition

Parenteral Nutrition (PN) delivers essential nutrients directly into the bloodstream, bypassing the digestive system. It is commonly used for individuals with severe digestive disorders or conditions that prevent normal nutrient absorption.
PN can be administered through two primary routes:
1. Central Parenteral Nutrition (CPN):
CPN involves delivering a high concentration of nutrients through a large vein. This is typically achieved using a Peripherally Inserted Central Catheter (PICC) or,...
468
Endocarditis IV: Nursing Management01:29

Endocarditis IV: Nursing Management

Infective endocarditis (IE) is a chronic infection of the heart's endocardium, primarily affecting the heart valves. A detailed nursing assessment for a patient with IE involves collecting subjective and objective data to ensure an accurate diagnosis and timely intervention.Subjective DataThe nurse gathers information about the patient's symptoms and complaints during the subjective assessment. Patients with infective endocarditis often report non-specific symptoms that can mimic other...
148
Cardiac Catheterization I: Pre-Procedure Overview01:28

Cardiac Catheterization I: Pre-Procedure Overview

Cardiac catheterization is an invasive diagnostic technique used to identify and evaluate structural and functional diseases of the heart and major blood vessels. This technique diagnoses congenital heart disease, coronary artery disease, valvular heart disease, and coronary spasms and assesses ventricular function. It helps guide treatment decisions, including the need for revascularization procedures like percutaneous coronary intervention (PCI) or coronary artery bypass grafting (CABG) and...
530
Cardiac Catheterization II: Right Heart Catheterization01:21

Cardiac Catheterization II: Right Heart Catheterization

Right Heart Catheterization: An OverviewRight heart catheterization is an invasive diagnostic procedure that measures right-sided cardiac and pulmonary artery pressures, calculates cardiac output, and identifies intracardiac shunts. It provides detailed hemodynamic data essential for diagnosing and managing various cardiovascular conditions, such as pulmonary hypertension.Access SitesCommon access sites for right heart catheterization include the internal jugular vein in the neck region, the...
387
Cardiac Catheterization IV: Nursing Management01:26

Cardiac Catheterization IV: Nursing Management

Nursing responsibilities before cardiac catheterization include:Assess for allergies and establish baseline health status.Before cardiac catheterization, assess the patient for allergies to contrast dye. Perform a comprehensive baseline assessment, including vital signs, heart and breath sounds, and a neurovascular assessment of the extremities, noting distal pulses, skin color, and temperature. Instruct the patient to fast for 8-12 hours before the procedure. Evaluate baseline laboratory...
403
Healthcare Associated Infections II: Preventive Measures01:22

Healthcare Associated Infections II: Preventive Measures

Essential infection prevention measures are based on the knowledge of the infection chain, the modes of transmission in healthcare settings, and the use of the best practices in all healthcare settings. Compulsory public reporting of healthcare-associated infection rates is needed to allow individuals and the community to make informed choices regarding selecting a healthcare facility.
The best practices for preventing healthcare-associated infections include hand hygiene, patient risk...
3.4K