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Detection of Human Leukocyte Antigen Biomarkers in Breast Cancer Utilizing Label-free Biosensor Technology

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Published on: March 24, 2015

Polymeric immunosensors for tumor detection.

Saloni Tandon¹, Suchi Mercy George², Robin McIntyre³

¹Biotechnology Lab, Center for Converging Technologies, University of Rajasthan, JLN Marg, Jaipur-302004, Rajasthan, India.

Biomedical Physics & Engineering Express

|January 13, 2021

Summary

This summary is machine-generated.

Early cancer detection using immunosensors is crucial for improving patient outcomes. This review highlights polymeric immunosensors for enhanced sensitivity and selectivity in identifying tumor biomarkers in body fluids.

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Last Updated: Nov 21, 2025

Detection of Human Leukocyte Antigen Biomarkers in Breast Cancer Utilizing Label-free Biosensor Technology

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Published on: March 24, 2015

Author Spotlight: Engineering Molecular Tools for Disease Detection and Imaging

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Multiplexed Barcoding Image Analysis for Immunoprofiling and Spatial Mapping Characterization in the Single-Cell Analysis of Paraffin Tissue Samples

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Published on: April 7, 2023

Area of Science:

Biomedical Engineering
Oncology
Analytical Chemistry

Background:

Cancer is a global health challenge with high mortality, often due to late diagnosis.
Accurate and timely detection of cancer is critical for effective management and treatment.
Tumor biomarkers in bodily fluids offer potential for early disease identification.

Purpose of the Study:

To review various tumor biomarkers and their detection methods.
To explore the application of immunosensors for sensitive biomarker detection.
To focus on advancements in polymeric immunosensors for improved cancer diagnostics.

Main Methods:

Literature review of tumor biomarkers and detection technologies.
Analysis of immunosensor principles and their role in diagnostics.
Investigation of polymeric materials (e.g., polypyrrole, polyaniline) in immunosensor development.

Main Results:

Immunosensors enable the detection of low concentrations of tumor biomarkers.
Polymeric materials enhance the sensitivity and selectivity of immunosensors.
Polymeric immunosensors offer potential for point-of-care cancer detection.

Conclusions:

Timely diagnosis via tumor biomarkers is key to managing cancer.
Immunosensors, particularly polymeric versions, show significant promise for early cancer detection.
Further research into polymeric immunosensors can lead to more efficient diagnostic tools.