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Cluster headache, beyond the pain: a comparative cross-sectional study.

Javier Díaz-de-Terán1,2,3, María Sastre-Real1,2, Luis Lobato-Pérez1,2

  • 1Department of Neurology, La Paz University Hospital, Madrid, Spain.

Neurological Sciences : Official Journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology
|January 13, 2021
PubMed
Summary

Cluster headache patients experience more allodynia and pain catastrophizing than healthy individuals. Anxiety and headache impact predict pain catastrophizing, highlighting the need for integrated care.

Keywords:
Central sensitizationCluster headacheComorbiditiesPrimary headacheQuality of life

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Area of Science:

  • Neurology
  • Pain Medicine
  • Psychology

Background:

  • Cluster headache (CH) is a debilitating neurological disorder.
  • Understanding the psychological impact and comorbidities in CH is crucial for effective management.

Purpose of the Study:

  • Compare allodynia, pain catastrophizing, and headache impact in CH patients versus controls.
  • Analyze the relationship between pain catastrophizing, psychological comorbidities, and quality of life in CH patients.

Main Methods:

  • Cross-sectional study involving 47 CH patients and 40 healthy controls.
  • Assessment of allodynia, pain catastrophizing, anxiety, depression, and quality of life using validated scales.

Main Results:

  • CH patients showed significantly higher scores for allodynia, pain catastrophizing, and headache impact compared to controls.
  • Significant correlations were found between pain catastrophizing, anxiety, depression, and quality of life in CH patients.
  • Anxiety and headache impact (HIT-6) were significant predictors of pain catastrophizing (adjusted R² = 0.52).

Conclusions:

  • CH is associated with increased allodynia, pain catastrophizing, and impaired quality of life.
  • Psychological comorbidities like anxiety and depression are closely linked to pain catastrophizing and reduced quality of life in CH.
  • A multidisciplinary approach is recommended for screening and managing these comorbidities in CH patients.