One-Pot Dual C-C Coupling Reaction via Site Selective Cascade Formation by PdII -Cryptate of an Amino-Ether
Sayan Sarkar1, Piyali Sarkar1, Sandip Munshi1
1School of Chemical Sciences, Indian Association for the Cultivation of Science (IACS), 2A and 2B Raja S.C. Mullick Road, Jadavpur, Kolkata, 700032, West Bengal, India.
Abstract:
Selectivity of aryl iodo over ethynyl iodo toward the Suzuki cross coupling reaction is explored by utilizing a palladium complex of amino-ether heteroditopic macrobicycle. Subsequently, unreacted ethynyl iodide undergoes homocoupling reaction in the same catalytic atmosphere, thereby representing a cascade dual C-C coupling reaction. Furthermore, this approach is extended for novel one-pot synthesis of unsymmetrical 1,3-diynes.
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