Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Metal-Organic Framework-Gated Biocatalysis Enables Triggered Depolymerization of Melt-Processed Polyesters.

Angewandte Chemie (International ed. in English)·2026
Same author

Enzymatic 1,4-addition of 2-hydroxy-3-keto-glucal for β-selective aryl-<i>C</i>-glycosylation of polyphenols.

Chemical communications (Cambridge, England)·2026
Same author

Integrative SAXS and AFM analysis of engineered carbohydrate-active enzyme assemblies with tunable spatial organization.

Protein science : a publication of the Protein Society·2026
Same author

Biomimetic Synthesis of Seven Halenaquinone Meroterpenoids.

Journal of the American Chemical Society·2026
Same author

A Modular Nucleoside Kinase Cascade for the Synthesis of Ribonucleoside Triphosphates.

Biotechnology and bioengineering·2026
Same author

Emerging porous materials for cell encapsulation.

Chemical Society reviews·2026
Same journal

Synthetic Porous Carbons for High-Energy, High-Power Supercapacitors.

Chemical reviews·2026
Same journal

Navigating Misfolded Terrain: ER-Associated Degradation of Membrane Proteins.

Chemical reviews·2026
Same journal

Ink Design for Printing Perovskite Solar Cells and Modules.

Chemical reviews·2026
Same journal

Advanced Single-Atom Catalysts for Thermal-Catalytic C1 Chemistry.

Chemical reviews·2026
Same journal

Copper-Dependent Polysaccharide Monooxygenases: Mechanism and Function.

Chemical reviews·2026
Same journal

To Biotic or Abiotic: Biohybrid Systems for Artificial Photosynthesis.

Chemical reviews·2026
See all related articles

Related Experiment Video

Updated: Nov 21, 2025

Author Spotlight: Exploring Self-Assembled MOF-Polymer Composites
06:48

Author Spotlight: Exploring Self-Assembled MOF-Polymer Composites

Published on: June 14, 2024

2.2K

Metal-Organic Framework-Based Enzyme Biocomposites.

Weibin Liang1, Peter Wied2, Francesco Carraro2

  • 1Department of Chemistry and Centre for Advanced Nanomaterials, The University of Adelaide, Adelaide, South Australia 5005, Australia.

Chemical Reviews
|January 13, 2021
PubMed
Summary
This summary is machine-generated.

Enzymes are useful in biotechnology but sensitive to harsh conditions. Metal-organic frameworks (MOFs) protect enzymes through encapsulation or binding, enhancing stability for industrial applications.

More Related Videos

Synthesis and Characterization of Functionalized Metal-organic Frameworks
11:27

Synthesis and Characterization of Functionalized Metal-organic Frameworks

Published on: September 5, 2014

48.7K
Author Spotlight: Advances in Evaluating Human Lung Epithelial Cells' Response to Metal-Organic Frameworks
04:53

Author Spotlight: Advances in Evaluating Human Lung Epithelial Cells' Response to Metal-Organic Frameworks

Published on: May 26, 2023

1.5K

Related Experiment Videos

Last Updated: Nov 21, 2025

Author Spotlight: Exploring Self-Assembled MOF-Polymer Composites
06:48

Author Spotlight: Exploring Self-Assembled MOF-Polymer Composites

Published on: June 14, 2024

2.2K
Synthesis and Characterization of Functionalized Metal-organic Frameworks
11:27

Synthesis and Characterization of Functionalized Metal-organic Frameworks

Published on: September 5, 2014

48.7K
Author Spotlight: Advances in Evaluating Human Lung Epithelial Cells' Response to Metal-Organic Frameworks
04:53

Author Spotlight: Advances in Evaluating Human Lung Epithelial Cells' Response to Metal-Organic Frameworks

Published on: May 26, 2023

1.5K

Area of Science:

  • Materials Science
  • Biotechnology
  • Enzymology

Background:

  • Enzymes offer efficient, selective, and sustainable biocatalysis.
  • Enzyme activity is compromised by thermal, pH, and chemical stressors due to their reliance on noncovalent interactions.
  • Metal-organic frameworks (MOFs) are porous materials that can protect enzymes.

Purpose of the Study:

  • To review methods for protecting enzymes using MOFs.
  • To explore strategies for creating enzyme/MOF composites.
  • To assess characterization techniques for MOF-immobilized enzymes.

Main Methods:

  • Enzyme encapsulation during MOF synthesis.
  • Enzyme infiltration into pre-formed MOF structures.
  • Enzyme surface binding to MOFs (covalent or noncovalent).

Main Results:

  • MOF integration protects enzymes from denaturing agents, high temperatures, non-native pH, and organic solvents.
  • Enzyme/MOF composites can be functionalized with additional materials for improved recovery or advanced applications.
  • Various characterization methods are employed to analyze MOF-immobilized enzymes.

Conclusions:

  • Enzyme/MOF biocomposites offer a robust platform for enzyme stabilization and application.
  • Further development requires interdisciplinary approaches combining materials chemistry and enzymology.
  • Standardized characterization is key to advancing the field of MOF-immobilized enzymes.