Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

COVID-19 and Tissue Engineering: What Have We Accomplished in the Past 5 Years?

Tissue engineering. Part A·2026
Same author

Implantable living materials autonomously deliver therapeutics using contained engineered bacteria.

Science (New York, N.Y.)·2026
Same author

Antibiotic Duration after Debridement and Implant Retention for Early Postoperative Spinal Implant Infections: A Multicenter Cohort Study.

Clinical infectious diseases : an official publication of the Infectious Diseases Society of America·2026
Same author

Lipid mobilization establishes metabolic tolerance and prevents autonomic collapse in infection.

bioRxiv : the preprint server for biology·2026
Same author

CORR Insights®: S1P Modulation via S1P Lyase Inhibition Enhances Bone Regeneration in a Murine Critical-size Defect Model of Atrophic Nonunion.

Clinical orthopaedics and related research·2026
Same author

Synthesis and Characterization of an Antimicrobial Honey-based Composite Bone Cement.

Clinical orthopaedics and related research·2026

Related Experiment Video

Updated: Nov 21, 2025

Antimicrobial Characterization of Advanced Materials for Bioengineering Applications
08:08

Antimicrobial Characterization of Advanced Materials for Bioengineering Applications

Published on: August 4, 2018

22.5K

Inherently Antimicrobial Biodegradable Polymers in Tissue Engineering.

Emma Watson1,2, Alexander M Tatara1,2, Dimitrios P Kontoyiannis3

  • 1Department of Bioengineering, Rice University, Houston, Texas 77005, Unites States.

ACS Biomaterials Science & Engineering
|January 14, 2021
PubMed
Summary
This summary is machine-generated.

Infection hinders tissue engineering. Inherently antimicrobial biodegradable polymers (IABPs) offer a solution by resisting infection as scaffolds degrade and new tissue forms, improving healing outcomes.

Keywords:
antimicrobialbiodegradablepolymertissue engineering

More Related Videos

Direct and Indirect Culture Methods for Studying Biodegradable Implant Materials In Vitro
14:49

Direct and Indirect Culture Methods for Studying Biodegradable Implant Materials In Vitro

Published on: April 15, 2022

5.4K
A Facile and Eco-friendly Route to Fabricate PolyLactic Acid Scaffolds with Graded Pore Size
13:46

A Facile and Eco-friendly Route to Fabricate PolyLactic Acid Scaffolds with Graded Pore Size

Published on: October 17, 2016

8.9K

Related Experiment Videos

Last Updated: Nov 21, 2025

Antimicrobial Characterization of Advanced Materials for Bioengineering Applications
08:08

Antimicrobial Characterization of Advanced Materials for Bioengineering Applications

Published on: August 4, 2018

22.5K
Direct and Indirect Culture Methods for Studying Biodegradable Implant Materials In Vitro
14:49

Direct and Indirect Culture Methods for Studying Biodegradable Implant Materials In Vitro

Published on: April 15, 2022

5.4K
A Facile and Eco-friendly Route to Fabricate PolyLactic Acid Scaffolds with Graded Pore Size
13:46

A Facile and Eco-friendly Route to Fabricate PolyLactic Acid Scaffolds with Graded Pore Size

Published on: October 17, 2016

8.9K

Area of Science:

  • Biomaterials Science
  • Regenerative Medicine
  • Polymer Chemistry

Background:

  • Tissue engineering strategies often combine cells with degradable scaffolds for tissue regeneration.
  • Scaffold or wound infection frequently leads to the failure of healing processes.
  • Developing infection-resistant scaffolds is crucial for successful tissue regeneration.

Purpose of the Study:

  • To review inherently antimicrobial biodegradable polymers (IABPs) for tissue engineering applications.
  • To discuss current platforms for IABP synthesis and their classification.
  • To highlight future research directions and challenges in the field of IABPs.

Main Methods:

  • Classification of IABPs based on monomeric components: traditional antimicrobials, naturally derived compounds, and novel synthetic antimicrobials.
  • Emphasis on the necessity of chemical synthesis validation and physicochemical characterization.
  • Requirement for rigorous in vitro and in vivo assays to confirm antimicrobial efficacy and biocompatibility.

Main Results:

  • IABPs offer a promising approach to prevent infection during tissue regeneration.
  • The review categorizes IABPs into three main groups based on their origin.
  • Validation and testing are critical steps for ensuring scaffold performance.

Conclusions:

  • IABPs represent a significant advancement in overcoming infection challenges in tissue engineering.
  • Further research into synthesis platforms and rigorous testing is essential for clinical translation.
  • The development of IABPs holds great potential for improving regenerative medicine outcomes.