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Myopericarditis and myositis in a patient with COVID-19: a case report

Asad Shabbir1, Christian Fielder Camm1, Andrew Elkington1

  • 1The Royal Berkshire Hospital, London Road, Reading RG1 5AN, UK.

European Heart Journal. Case Reports
|January 14, 2021
PubMed

Insights

This case study reports the first instance of concurrent myopericarditis and myositis linked to COVID-19. Treatment with colchicine, NSAIDs, and steroids effectively reduced inflammation and improved symptoms.

Area of Science:

  • Cardiology
  • Neurology
  • Infectious Diseases

Background:

  • Concurrent myopericarditis and myositis can occur in patients with systemic inflammatory diseases.
  • This case highlights myopericarditis and myositis associated with COVID-19, notably without respiratory symptoms.

Purpose of the Study:

  • To report the first case of concurrent myopericarditis and myositis associated with COVID-19.
  • To describe the clinical presentation, diagnostic findings, and treatment outcomes.

Main Methods:

  • A middle-aged female with hypertension and prior myopericarditis presented with chest pain.
  • Diagnostic workup included ECG, echocardiography, CT thorax, cardiac MRI, and thigh MRI.
  • SARS-CoV-2 infection was confirmed despite the absence of respiratory symptoms.

Main Results:

  • The patient exhibited ECG and echocardiographic features of myopericarditis.
  • She developed bilateral leg weakness with elevated creatine kinase (CK), confirmed as myositis via MRI.
  • Cardiac MRI confirmed myopericarditis.

Conclusions:

  • This is the first reported case of concurrent myopericarditis and myositis associated with COVID-19.
  • Conventional therapy (colchicine, NSAIDs, glucocorticoids) led to symptom improvement and reduced inflammatory markers.
Abstract

Keywords:
COVID-19Case reportMyopericarditisMyositisSARS-CoV-2

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