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Implantation of Total Artificial Heart in Congenital Heart Disease
Published on: July 18, 2014
A case report of a rare cardiac complication in novel coronavirus disease
Alireza Malekrah1, Alireza Fatahian1
1Cardiovascular Research Center, Mazandaran University of Medical Science, Farah Abad Road, Sari, Mazandaran Province, Iran.
Insights
This case study highlights severe cardiac arrhythmias, including persistent left bundle branch block and atrial fibrillation, as a potential irreversible complication of COVID-19, emphasizing the virus
Area of Science:
- Cardiology
- Infectious Diseases
- Internal Medicine
Background:
- The global spread of COVID-19 has revealed numerous unknown complications.
- Cardiac involvement and arrhythmias in COVID-19 patients remain poorly understood.
Purpose of the Study:
- To report a case of severe cardiac conduction abnormalities in a patient with COVID-19.
- To investigate the potential for irreversible cardiac damage caused by the virus.
Main Methods:
- A 71-year-old male with COVID-19 symptoms underwent diagnostic testing (chest CT, PCR).
- Cardiac involvement was monitored, including atrioventricular block and left bundle branch block (LBBB).
- The patient developed atrial fibrillation with bradycardia; pacemaker implantation was considered after conservative management failed.
Main Results:
- COVID-19 diagnosis was confirmed.
- The patient experienced progressive cardiac conduction abnormalities, including fixed LBBB and atrial fibrillation with bradycardia.
- Despite a 14-day waiting period, the atrioventricular block did not resolve, necessitating further intervention.
Conclusions:
- COVID-19, primarily respiratory, can cause significant cardiac complications.
- Arrhythmias in COVID-19 may stem from myocardial inflammation, hypoxia, or electrolyte imbalances.
- This case suggests SARS-CoV-2 can preferentially and irreversibly damage the cardiac conduction system.
Background:
Since late 2019, the outbreak of COVID-19 has rapidly spread worldwide. As it is a newly emerged disease, many of its manifestations and complications are unknown to us. Cardiac involvement and arrhythmias are another aspect of the disease about which very little is known.
Case Summary:
A 71-year-old male patient presented at the Emergency Department complaining of fever, a dry cough, and dyspneoa. He was admitted due to these symptoms suggestive of COVID-19, and a chest CT and PCR test confirmed the diagnosis. During admission, cardiac involvement was detected, i.e. second-degree atrioventricular block with intermittent left bundle branch block (LBBB) which progressed to fixed LBBB and eventually developed into atrial fibrillation/flutter with bradycardia. Both cardiac troponin and echocardiographic findings for detecting myocarditis were negative. We waited 14 days for resolution of atrioventricular block before permanent pacemaker implantation, but the condition still did not improve after the waiting period.
Discussion:
COVID-19 is mainly a respiratory infection but cardiac involvement is not uncommon in the course of the disease. Arrhythmia, during this infection, seems to be caused by an inflammatory response in the myocardium, electrolyte disturbances, and hypoxia; the course of the disease in our case study shows that the virus can preferentially and irreversibly involve the cardiac conduction system.
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