A case report of a rare cardiac complication in novel coronavirus disease

Alireza Malekrah1, Alireza Fatahian1

  • 1Cardiovascular Research Center, Mazandaran University of Medical Science, Farah Abad Road, Sari, Mazandaran Province, Iran.

Insights

This case study highlights severe cardiac arrhythmias, including persistent left bundle branch block and atrial fibrillation, as a potential irreversible complication of COVID-19, emphasizing the virus

Area of Science:

  • Cardiology
  • Infectious Diseases
  • Internal Medicine

Background:

  • The global spread of COVID-19 has revealed numerous unknown complications.
  • Cardiac involvement and arrhythmias in COVID-19 patients remain poorly understood.

Purpose of the Study:

  • To report a case of severe cardiac conduction abnormalities in a patient with COVID-19.
  • To investigate the potential for irreversible cardiac damage caused by the virus.

Main Methods:

  • A 71-year-old male with COVID-19 symptoms underwent diagnostic testing (chest CT, PCR).
  • Cardiac involvement was monitored, including atrioventricular block and left bundle branch block (LBBB).
  • The patient developed atrial fibrillation with bradycardia; pacemaker implantation was considered after conservative management failed.

Main Results:

  • COVID-19 diagnosis was confirmed.
  • The patient experienced progressive cardiac conduction abnormalities, including fixed LBBB and atrial fibrillation with bradycardia.
  • Despite a 14-day waiting period, the atrioventricular block did not resolve, necessitating further intervention.

Conclusions:

  • COVID-19, primarily respiratory, can cause significant cardiac complications.
  • Arrhythmias in COVID-19 may stem from myocardial inflammation, hypoxia, or electrolyte imbalances.
  • This case suggests SARS-CoV-2 can preferentially and irreversibly damage the cardiac conduction system.
Abstract

Related Concept Videos

Coronary Artery Disease III: Clinical Manifestations01:30

Coronary Artery Disease III: Clinical Manifestations

Coronary Artery Disease (CAD) is a primary health risk worldwide, leading to significant morbidity and mortality. The condition arises from the buildup of atherosclerotic plaques within the coronary arteries, resulting in diminished blood supply to the heart muscle.The clinical manifestations of CAD vary widely, from asymptomatic stages to severe, life-threatening conditions. Understanding these manifestations is crucial for early diagnosis and effective management.Angina Pectoris: The Warning...
153
Cardiomyopathy IV: Restrictive Cardiomyopathy01:29

Cardiomyopathy IV: Restrictive Cardiomyopathy

Restrictive cardiomyopathy (RCM) is a rare heart muscle disease characterized by impaired ventricular filling due to stiffened ventricular walls, leading to significant diastolic dysfunction.EtiologyRestrictive cardiomyopathy can arise from both inherited and acquired diseases, many of which are systemic. It is categorized into four main types: infiltrative, storage, non-infiltrative, and endomyocardial diseases.Infiltrative diseases, such as amyloidosis, lead to RCM by depositing amyloid...
200
Introduction Cardiac Emergencies01:30

Introduction Cardiac Emergencies

Cardiac emergencies are critical situations involving the heart that require immediate medical intervention to prevent severe complications or death. These emergencies often arise from underlying heart conditions that impair the heart's ability to function correctly.Types of Cardiac EmergenciesThe most common types of cardiac emergencies include Acute Coronary Syndrome (ACS), myocardial infarction (MI), cardiac arrest, and heart failure.Acute Coronary Syndrome (ACS)Acute Coronary Syndrome (ACS)...
171
Cardiomyopathy II: Dilated Cardiomyopathy01:30

Cardiomyopathy II: Dilated Cardiomyopathy

Dilated cardiomyopathy, or DCM, is a progressive myocardial disorder characterized by ventricular chamber dilation and contractile dysfunction.EtiologyVarious factors can cause DCM, including hypertension and heavy alcohol intake, which contribute to the weakening and enlargement of the heart muscle. Viral infections, such as Coxsackievirus B, adenoviruses, and influenza, can lead to DCM by causing inflammation and damage to heart tissue. Certain chemotherapeutic agents, including daunorubicin,...
152
Cardiomyopathy I: Introduction and Classification01:25

Cardiomyopathy I: Introduction and Classification

Cardiomyopathy, or CMP, is a group of diseases affecting the myocardial structure, impairing its ability to pump blood effectively. This condition can lead to arrhythmias, heart failure, or sudden cardiac death.Cardiomyopathies are classified into primary and secondary categories:Primary Cardiomyopathy refers to conditions involving only the heart muscle that are often idiopathic (of unknown cause) or genetic. They primarily affect the myocardium without the involvement of other systemic...
215
Imbalances in Cardiac Output01:26

Imbalances in Cardiac Output

The heart's primary function is to pump blood throughout the body, maintaining a balance between blood sent out (cardiac output) and blood returning (venous return). If this balance is disrupted, it can result in congestive heart failure (CHF), a severe condition where the heart becomes an inefficient pump, leading to inadequate blood circulation.
CHF can occur due to the failure of either side of the heart. Left-side failure leads to pulmonary congestion—the right side continues to send...
2.0K