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Adopted individuals' interest in elective genomic testing.

Jessica Edgar1, Annie Bao2, Tara Maga2,3

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Adoptees show greater interest in elective genomic testing (EGT) for family health history information. Social identity influences their motivation for genetic testing, highlighting unique needs for healthcare providers.

Keywords:
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Area of Science:

  • Genetics
  • Genomic Medicine
  • Population Health

Background:

  • Adoptees often lack comprehensive family health history (FHH).
  • Elective genomic testing (EGT) offers a pathway for adoptees to access genetic health risk information.
  • Understanding adoptee motivations for EGT is crucial for healthcare provision.

Purpose of the Study:

  • To assess adoptees' interest in, motivations for, and perceived utility of elective genomic testing (EGT).
  • To compare EGT interest and motivations between adoptees and non-adoptees.
  • To investigate the role of social identity in adoptees' genetic testing motivations.

Main Methods:

  • Anonymous online survey administered to adult adoptees and non-adoptees.
  • Inclusion of a validated measure of social identity to assess its impact on testing interest.
  • Analysis of interest, motivations, perceived utility, and willingness to pay for EGT.

Main Results:

  • Adoptees exhibited significantly higher interest in EGT compared to non-adoptees (OR 5.0).
  • Key motivations for adoptees included curiosity and desire for information relevant to descendants.
  • Social identity significantly mediated the relationship between adoption status and testing motivation.

Conclusions:

  • Healthcare providers can better meet adoptees' needs by understanding their unique motivations for EGT.
  • Social identity is a critical factor influencing adoptees' engagement with genetic testing.
  • EGT can address critical gaps in FHH for the adoptee population.