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[Mechanism of the antimutagenic action of dibunol]
Abstract:
In experiments with cultured V-79 Chinese hamster cells a study was made of the influence of dibunol on the level of gamma-radiation-induced micronuclei and sedimentation properties of cell nucleoids during ultracentrifugation in a neutral sucrose gradient. Protection of DNA molecule against the effects of both primary and secondary damages was found to be involved in the mechanism of the protective action of dibunol.