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[Hydrochlorothiazide-induced lung edema with shock].
Schweizerische Medizinische Wochenschrift
|January 31, 1988
Summary
Hydrochlorothiazide/amiloride can cause rare but dangerous pulmonary edema and shock. This case highlights a serious side effect of a commonly prescribed diuretic.
Area of Science:
- Cardiology
- Pulmonology
- Pharmacology
Background:
- Hydrochlorothiazide/amiloride is a widely prescribed diuretic for managing hypertension and edema.
- Pulmonary edema is a serious condition characterized by fluid accumulation in the lungs.
Observation:
- A 74-year-old woman experienced acute pulmonary edema and shock after taking a single tablet of hydrochlorothiazide/amiloride.
- The patient's symptoms and clinical course were consistent with drug-induced pulmonary edema.
Findings:
- This case represents a rare but significant adverse reaction to hydrochlorothiazide/amiloride.
- Literature review identified 14 similar cases of hydrochlorothiazide-induced pulmonary edema.
Implications:
- Clinicians should be aware of this potentially life-threatening side effect associated with hydrochlorothiazide/amiloride.
- Prompt recognition and management are crucial for patients presenting with these symptoms after diuretic use.
- Further research may be warranted to understand the mechanism and risk factors for this adverse event.