Related Experiment Video
Updated: Nov 21, 2025

A Method for Manipulating Blood Glucose and Measuring Resulting Changes in Cognitive Accessibility of Target Stimuli
Published on: August 12, 2016
Adaptive fractional-order blood glucose regulator based on high-order sliding mode observer
Hadi Delavari1, Hamid Heydarinejad1, Dumitru Baleanu2,3
1Department of Electrical Engineering, Hamedan University of Technology, Hamedan 65155, Iran.
Abstract:
Type I diabetes is described by the destruction of the insulin-producing beta-cells in the pancreas. Hence, exogenous insulin administration is necessary for Type I diabetes patients. In this study, to estimate the states that are not directly available from the Bergman minimal model a high-order sliding mode observer is proposed. Then fractional calculus is combined with sliding mode control (SMC) for blood glucose regulation to create more robustness performance and make more degree of freedom and flexibility for the proposed method. Then an adaptive fractional-order SMC is proposed. The adaptive SMC protect controller against disturbance and uncertainties while the fractional calculus provides robust performance. Numerical simulation verifies that the proposed controllers have better performance in the presence of disturbance and uncertainties without chattering.
Related Concept Videos
PD Controller: Design
Designing a continuous-data controller requires selecting and linking components like adders and integrators, which are fundamental in Proportional,...
Second Order systems II
Feedback Loops
PI Controller: Design
Hormones Regulating Blood Glucose
In addition to accelerating glucose uptake and utilization, insulin has...
Second Order systems I
By reinterpreting the system, one can derive the closed-loop transfer function, which...

