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Patch grafting the renal pelvis and ureteropelvic junction. A comparative study in pigs using lyophilized dura mater
P L Royce1, P E Zimmern, J B deKernion
1Department of Surgery, UCLA School of Medicine.
Urological Research
|January 1, 1988
Abstract:
Lyophilized dura mater (Lyodura) and autogenous free peritoneum were compared in the replacement of the partially resected renal pelvis and uretero-pelvic junction (UPJ) in the pig. The Lyodura and peritoneum grafts were both progressively resorbed, and replaced by fibroblasts which formed a mature scar lined by transitional epithelium, but without smooth muscle regeneration. Lyodura was found to be superior to free peritoneum with a longer time before resorption of the graft, less intense inflammatory reaction, absence of metaplastic bone formation, less risk of urine leak and greater ease of surgical manipulation.