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Updated: Aug 14, 2026

An Experimental Paradigm for the Prediction of Post-Operative Pain (PPOP)
Published on: January 27, 2010
Patient-controlled analgesia using butorphanol for postoperative pain relief: an open-label study
D P Wermeling1, T S Foster, E A Farrington
1Drug Product Evaluation Unit, College of Pharmacy, University of Kentucky Medical Center, Lexington.
Abstract:
Patient-controlled analgesia (PCA) has been studied extensively for the treatment of postoperative pain using narcotic analgesics. Butorphanol, a nonnarcotic injectable analgesic, has not previously been investigated using this drug delivery mechanism. Twenty-five patients undergoing general abdominal surgery and general anesthesia used a PCA device with butorphanol as the analgesic agent. Most patients (84%) were able to obtain excellent postoperative pain relief. The role of butorphanol in the management of postoperative pain should be expanded to include patient-controlled drug delivery.
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