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Deep learning for intelligent diagnosis in thyroid scintigraphy.

Tingting Qiao1, Simin Liu1, Zhijun Cui2

  • 1Department of Nuclear Medicine, Shanghai Tenth People's Hospital, Tongji University School of Medicine, Shanghai, China.

The Journal of International Medical Research
|January 15, 2021
PubMed
Summary
This summary is machine-generated.

Deep learning models show high accuracy in diagnosing thyroid diseases via scintigraphy. These AI tools assist nuclear medicine residents, significantly speeding up diagnostic times for conditions like Graves' disease.

Keywords:
Graves’ diseaseIntelligent diagnosisdeep learningdiagnostic performancenuclear medicine residentssubacute thyroiditisthyroid diseasethyroid scintigraphy

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Area of Science:

  • Medical Imaging
  • Artificial Intelligence
  • Endocrinology

Background:

  • Thyroid scintigraphy is crucial for diagnosing thyroid diseases.
  • Current diagnostic processes can be time-consuming and require expert interpretation.

Purpose of the Study:

  • To develop deep learning (DL) models for enhanced accuracy and efficiency in thyroid disease diagnosis using scintigraphy.
  • To evaluate the performance of different DL architectures (AlexNet, VGGNet, ResNet).

Main Methods:

  • DL models were constructed using AlexNet, VGGNet, and ResNet architectures with transfer learning.
  • Model performance was assessed using recall, precision, NPV, specificity, accuracy, and F1-score.
  • Diagnostic performance and speed were compared between DL models and nuclear medicine residents.

Main Results:

  • DL models achieved high performance metrics, with scores ranging from 73.33% to 97.00%.
  • All models demonstrated strong inter-rater reliability (Kappa > 0.710).
  • Models were significantly faster (400-600x) than residents and aided diagnostic accuracy, particularly the ResNet model.

Conclusions:

  • Deep learning models are effective tools for the diagnostic assessment of thyroid scintigraphy.
  • These AI models can assist nuclear medicine residents in diagnosing Graves' disease and subacute thyroiditis.
  • DL integration promises to improve efficiency and potentially accuracy in thyroid disease diagnostics.