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Updated: Nov 21, 2025
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Leveraging Turbidity and Thromboelastography for Complementary Clot Characterization
Published on: June 4, 2020
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Thromboelastogram to Detect Hypercoagulability in Critically Ill COVID-19 Patients: Has Its Time Come?
1Department of Critical Care Medicine, Apollo Hospitals, Chennai, Tamil Nadu, India.
Summary
Thromboelastogram (TEG) may help detect hypercoagulability in critically ill COVID-19 patients. Further research is needed to confirm its clinical utility in managing these complex cases.
Area of Science:
- Critical care medicine
- Hematology
- Infectious diseases
Background:
- Critically ill COVID-19 patients frequently exhibit a hypercoagulable state, increasing the risk of thrombotic complications.
- Traditional coagulation tests may not fully capture the complex hemostatic abnormalities seen in severe COVID-19.
- Thromboelastogram (TEG) offers a comprehensive assessment of clot formation and lysis.
Discussion:
- This article discusses the potential role of Thromboelastogram (TEG) in identifying hypercoagulability in critically ill patients with COVID-19.
- It explores whether TEG can provide valuable insights beyond standard coagulation assays for guiding treatment.
- The promptness and accuracy of TEG in reflecting the dynamic changes in coagulation during COVID-19 are considered.
Key Insights:
- Thromboelastogram (TEG) shows promise in detecting hypercoagulability, a common issue in severe COVID-19.
- Its ability to provide a global view of coagulation kinetics may aid in risk stratification.
- The clinical utility of TEG in guiding anticoagulant therapy for COVID-19 requires further investigation.
Outlook:
- Future studies should focus on prospective trials to validate TEG's predictive value for thrombotic events in COVID-19.
- Standardization of TEG protocols and interpretation in the context of COVID-19 is crucial.
- Integrating TEG data into clinical decision-making could potentially optimize patient management and improve outcomes.
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