Related Experiment Video
Updated: Nov 21, 2025

Systematic Assessment of Mammalian Skull Specimens for Dental and Temporomandibular Joint Pathology
Published on: August 22, 2022
Relationship between Pathological Occlusal Changes and the Signs and Symptoms of Temporomandibular Dysfunction
Ana de Lourdes Sá de Lira1, Maria Karen Vasconcelos Fontenele1
1Department of Pediatric Dentistry and Orthodontics, Universidade Estadual do Piauí - UESPI, Area of Integrated Clinic, Parnaíba, Piauí, Brazil.
Objective:
This study aimed to investigate whether there is a correlation between pathological occlusal changes and the signs and symptoms of temporomandibular dysfunction (TMD).
Methods:
This cross-sectional, quantitative, non-randomized clinical trial was conducted on 150 participants. We examined adult patients of both genders with occlusal interference, malocclusion and dental absence in the posterior region of the dental arch that were associated or not associated with painful symptoms. The questionnaire was administered, and the intra- and extra-oral clinical examination was performed on each patient, including the evaluation of the temporomandibular joint (TMJ) to investigate the presence of dysfunction.
Results:
The mean age of the participants was 33 years (±2.3), and 103 (68.7%) of them were women and 47 (31.3%) were men. Tooth loss and malocclusion were more prevalent in females. Tooth loss showed a statistically significant association with all the signs and symptoms of TMD (p=0.02). Patients with multiple teeth losses experienced preauricular pain during mandibular opening and closing. There was no association between malocclusion with tooth loss and the signs and symptoms of TMD in 65 patients (p>0.05).
Conclusion:
Only in the patients with Class II malocclusion there was a significant association with 2 signs of TMD (crackling and bruxism). There was no association between malocclusion and tooth loss with the signs and symptoms of TMD. The signs and symptoms of TMD were more frequent in the patients who presented multiple teeth loss without malocclusion.
Related Concept Videos
Assessment of the Mouth
Mouth Inspection
The inspection begins with visually examining the mouth for symmetry, color, and size.
Teeth
In the bud stage, the tooth germ (an aggregation of cells) starts to form in the developing jawbone. During the cap stage, the tooth germ differentiates into enamel organ, dental papilla, and dental sac, which will later develop into the tooth's enamel, dentin...
Tooth Anatomy
The Crown, Neck, and Root
The visible part of the tooth is referred to as the crown. It's covered by enamel, the hardest substance in the human body. The crown is uniquely shaped for each type of tooth, allowing for different functions such as cutting, tearing, or...
Psychosexual Stages of Personality: Oral
Weaning, typically occurring...
Oppositional Defiant Disorder
Diagnostic Criteria and...

