Related Experiment Video
Updated: Nov 21, 2025
08:53
Models of Murine Vaginal Colonization by Anaerobically Grown Bacteria
Published on: May 25, 2022
4.2K
Probiotics for preventing recurrent bacterial vaginosis
1Lauren Webb is an assistant professor in the PA program at Lipscomb University in Nashville, Tenn. The author has disclosed no potential conflicts of interest, financial or otherwise.
Summary
Oral or vaginal probiotics show promise in treating recurrent bacterial vaginosis (BV). While many studies demonstrate reduced BV recurrence, optimal probiotic use requires further investigation.
Area of Science:
- Microbiology
- Gynecology
- Infectious Diseases
Background:
- Bacterial vaginosis (BV) is a common vaginal condition with high recurrence rates.
- Current treatments for BV have limitations, driving interest in alternative therapies.
Purpose of the Study:
- To evaluate the efficacy of probiotics in treating and preventing recurrent bacterial vaginosis.
- To synthesize findings from studies investigating various probiotic interventions for BV.
Main Methods:
- Systematic review and meta-analysis of existing studies on oral and vaginal probiotics for BV.
- Analysis of different probiotic strains, dosages, administration routes, and treatment durations.
Main Results:
- Multiple studies indicate that probiotics, administered orally or vaginally, can significantly reduce BV recurrence.
- Observed efficacy varies based on probiotic type, dose, and treatment protocol.
Conclusions:
- Probiotics represent a viable option for managing recurrent bacterial vaginosis.
- Further research is essential to establish standardized protocols, including optimal dosage, strain selection, and duration of therapy, potentially in conjunction with antibiotics.
Related Concept Videos
01:17Drugs for Treatment of Diarrhea-Predominant IBS
433
Diarrhea-predominant irritable bowel syndrome (IBS-D) is a subtype of IBS characterized primarily by frequent, loose, or watery stools, abdominal pain, and abdominal discomfort. Therapeutic approaches to managing IBS-D include dietary changes, stress management techniques, and pharmaceutical interventions.
Two specific drugs used in the treatment are alosetron (Lotronex) and eluxadoline (Viberzi). Alosetron, a 5-HT3 antagonist, works by slowing the movement of stools in the gut, reducing bowel...
Two specific drugs used in the treatment are alosetron (Lotronex) and eluxadoline (Viberzi). Alosetron, a 5-HT3 antagonist, works by slowing the movement of stools in the gut, reducing bowel...
433
01:16Treating Helicobacter pylori in Peptic Ulcers: Antimicrobial Therapy
756
Helicobacter pylori, a resilient gram-negative bacterium, can thrive in the stomach's harsh, acidic environment. Infection with H. pylori leads to a cascade of events within the stomach lining. One of the critical disruptions caused by this bacterium is the interference with somatostatin production, a hormone responsible for regulating acid secretion. This interference tips the balance, escalating acid secretion and diminishing bicarbonate levels. This imbalance compromises the defensive...
756
01:29Bacterial Flora of the Large Intestine
990
The gut microbiome is formed by a vast and diverse community of bacteria that colonizes our large intestine. These bacteria start residing in the gut from birth and continue diversifying throughout life, influenced by factors such as diet, lifestyle, and stress. The gut bacterial community also includes bacteria from food and those that enter the colon through the anus.
The normal gut flora of the colon plays a critical role in generating essential vitamins such as vitamins K, B5, and B7.
The normal gut flora of the colon plays a critical role in generating essential vitamins such as vitamins K, B5, and B7.
990
01:18Surface Membrane Barriers
2.0K
The skin and mucous membranes serve as the primary line of defense against pathogens by providing both physical and chemical protection. These barriers are essential in preventing the entry and establishment of microbes, thereby maintaining the integrity of the host.
The outer layer of the skin, the epidermis, is a robust barrier comprising layers of closely packed keratinized cells. This dense arrangement prevents microbes from penetrating the body. The periodic shedding of epidermal cells...
The outer layer of the skin, the epidermis, is a robust barrier comprising layers of closely packed keratinized cells. This dense arrangement prevents microbes from penetrating the body. The periodic shedding of epidermal cells...
2.0K
01:18Drugs Affecting GI Tract Motility: Antimicrobials as Antidiarrheal Agents
306
Acute diarrhea, a common gastrointestinal disturbance, is characterized by the rapid evacuation of fluid stools, leading to an excessive weight in fluid. This condition typically arises from disorders affecting intestinal water and electrolyte transport. It can be triggered by an increased osmotic load within the intestine, excessive secretion of electrolytes and water, mucosal exudation of protein and fluid, or altered intestinal motility. The primary risks of acute diarrhea are dehydration...
306
01:21Drugs for Treatment of Constipation-Predominant IBS
487
Pharmacological therapies for IBS-C are designed to alleviate abdominal discomfort and enhance bowel function. In patients with IBS-C, fiber supplements may help soften stools and decrease straining, but may also lead to increased gas production and bloating. Osmotic laxatives like milk of magnesia are frequently used to soften stools and increase stool frequency in IBS-C patients. In addition, two drugs approved for use in severe IBS-C adult cases are linaclotide (Linzess) and lubiprostone...
487