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Published on: May 31, 2021
Management of pediatric allergic reaction: Practice patterns of Canadian pediatric emergency physicians
Caitlin Prendergast1,2, Amy C Plint1,2,3, Ken Tang4
1Division of Emergency Medicine, CHEO, Ottawa, ON.
Insights
Pediatric emergency physicians accurately recognized anaphylaxis but showed gaps in management, particularly in recognizing cases without typical symptoms and consistently prescribing epinephrine. These findings highlight areas for improvement in pediatric anaphylaxis care.
Area of Science:
- Pediatric Emergency Medicine
- Allergy and Immunology
- Clinical Practice Guidelines
Background:
- Anaphylaxis is a severe, potentially fatal allergic reaction with increasing incidence.
- Existing literature suggests deficiencies in anaphylaxis recognition and management.
- Gaps in pediatric anaphylaxis care require examination.
Purpose of the Study:
- To assess the extent of anaphylaxis diagnosis and management gaps in Canadian pediatric emergency medicine.
- To identify specific areas of deficiency in recognizing and treating anaphylaxis among pediatric emergency physicians.
Main Methods:
- A self-administered survey was distributed to physicians in the Pediatric Emergency Research Canada (PERC) network.
- The survey included four clinical scenarios to evaluate diagnosis and management of anaphylaxis based on National Institute of Allergy and Infectious Diseases (NIAID) criteria.
- Questions covered diagnosis, treatment with epinephrine, observation times, and physician demographics.
Main Results:
- A 71% response rate (152/214) was achieved.
- Anaphylaxis recognition rates were high (93-99%) for NIAID criteria.
- Epinephrine prescription varied (72-96%), with 54% of respondents consistently treating indicated cases.
Conclusions:
- While most pediatric emergency physicians recognize anaphylaxis, significant management gaps persist.
- Key deficiencies include recognizing anaphylaxis without urticaria or pulmonary symptoms and consistent epinephrine use.
- Addressing these management gaps is crucial for improving care for pediatric patients experiencing anaphylaxis.
Objectives:
Anaphylaxis is a severe allergic reaction that can be life-threatening. The literature indicates that the incidence of anaphylaxis is increasing and that there are deficiencies in both recognition and management. We aimed to examine the magnitude of these gaps in Canadian pediatric emergency medicine (PEM).
Methods:
We conducted a self-administered survey of the Pediatric Emergency Research Canada (PERC) physician database. The survey tool was developed through a literature review to identify recurring themes of gaps in anaphylaxis diagnosis and management. The final tool contained four scenarios; three scenarios featured each of the National Institute of Allergy and Infectious Diseases (NIAID) anaphylaxis criteria, separately, and a fourth case of non-anaphylactic allergy. Multiple-choice questions associated with each scenario addressed diagnosis, management, and disposition. Additional questions focused on epinephrine prescribing, observation durations, and respondent demographics.
Results:
Of the 214 members invited to participate in the survey, 152 (71%) responded. Anaphylaxis was accurately recognized 93%, 82%, and 99% of the time for the NIAID criteria one through three, respectively. When anaphylaxis was recognized, epinephrine was prescribed for each case 96%, 95%, and 72% of the time, respectively. Of all respondents, 115 (76%) accurately diagnosed all three cases of anaphylaxis and 82 (54%) treated anaphylaxis with epinephrine each time it was indicated.
Conclusion:
Most respondents recognized cases of anaphylaxis; however, a substantial number demonstrated gaps in management that may adversely impact this vulnerable population. The recognition of anaphylaxis without urticaria or pulmonary findings and treatment of anaphylaxis with epinephrine, where indicated, were the main gaps identified.
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