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Updated: Nov 21, 2025

Use of Label-free Optical Biosensors to Detect Modulation of Potassium Channels by G-protein Coupled Receptors

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Published on: February 10, 2014

Slotted photonic crystal fiber-based plasmonic biosensor.

Hasan Sarker, Mohammad Faisal, Md Aslam Mollah

|January 15, 2021

Summary

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A novel slotted photonic crystal fiber (PCF) biosensor demonstrates high sensitivity for detecting biomolecules. This cost-effective sensor offers superior performance for various sensing applications.

Area of Science:

Photonics
Nanotechnology
Biomedical Engineering

Background:

Photonic crystal fibers (PCFs) offer advanced optical properties beyond conventional fibers.
Plasmonic sensors are crucial for detecting analytes with high sensitivity.

Purpose of the Study:

To numerically investigate a simplified, highly sensitive slotted PCF-based plasmonic biosensor.
To optimize sensor performance and analyze parameter effects for enhanced detection capabilities.

Main Methods:

Utilizing the finite element method for numerical simulation of the slotted PCF.
Employing an interrogation method to record sensor performance metrics.
Performing resonance wavelength curve fitting for sensor optimization.

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Last Updated: Nov 21, 2025

Use of Label-free Optical Biosensors to Detect Modulation of Potassium Channels by G-protein Coupled Receptors

Use of Label-free Optical Biosensors to Detect Modulation of Potassium Channels by G-protein Coupled Receptors

Published on: February 10, 2014

Trapping of Micro Particles in Nanoplasmonic Optical Lattice

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Published on: September 5, 2017

Fabrication of 1-D Photonic Crystal Cavity on a Nanofiber Using Femtosecond Laser-induced Ablation

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Published on: February 25, 2017

Main Results:

Achieved maximum wavelength sensitivity of 22000 nm/RIU and amplitude sensitivity of 1782.56 RIU⁻¹.
Obtained a maximum wavelength resolution of 4.54×10⁻⁶ RIU⁻¹ for the y-polarized mode.
Demonstrated superior sensitivity compared to other PCF-based sensors.

Conclusions:

The designed slotted PCF plasmonic biosensor is simple, cost-effective, and easy to fabricate.
Its high sensitivity and symmetric structure make it suitable for refractive index detection and biochemical/biomolecule identification.