Random laser emission from whole blood as the active medium

Area of Science:

• Biophotonics
• Laser Physics
• Materials Science

Background:

• Random lasers (RLs) offer unique properties for light generation.
• Whole blood (WB) has not been explored as an active medium for RL emission.

Purpose of the Study:

• To demonstrate the feasibility of multimode random laser emission using fresh whole blood (WB) as the active medium.
• To adapt established RL principles for biological samples.

Main Methods:

• Utilized a principle adapted from rhodamine 6G (R6G) random laser emission.
• Incorporated SiO2 particles suspended in an isotonic solvent to induce random feedback.
• Investigated stimulated emission of radiation in fresh WB under specific conditions.

Main Results:

• Achieved random laser emission from fresh whole blood (WB) at wavelengths of 969 nm and 437 nm, with sub-3 nm bandwidth.
• Rhodamine 6G (R6G) random laser emission was observed with a 2 nm bandwidth centered at 567 nm.
• The pumping energy threshold for RL emission from WB was found to be consistent with that of R6G-RL, validating the findings.

Conclusions:

• Fresh whole blood (WB) can serve as an active medium for random laser emission.
• The study establishes a proof of concept for using biological fluids in random laser applications.
• Further research may explore optimized conditions for enhanced RL properties from blood.