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Photopatch Testing in New Zealand: A 12-Year Retrospective Review
Yena Kim1, Denesh C Patel, Deborah Greig
1From the Department of Dermatology, Greenlane Clinical Centre, Auckland, New Zealand.
Dermatitis : Contact, Atopic, Occupational, Drug
|January 15, 2021
Summary
Photopatch testing in New Zealand identified promethazine and benzophenone-3 as the primary photoallergens. This study highlights the importance of photopatch testing for diagnosing photoallergic contact dermatitis.
Area of Science:
- Dermatology
- Photobiology
- Allergology
Background:
- Limited data exists on common photoallergens in New Zealand, a region with high ultraviolet radiation exposure.
- Access to photopatch testing is restricted, with limited availability in specialized clinics.
Purpose of the Study:
- To evaluate the experience and outcomes of photopatch testing in New Zealand.
- To identify common photoallergens and diagnoses in patients undergoing photopatch testing.
Main Methods:
- A retrospective review of patients who underwent photopatch testing between 2008 and 2019 at a tertiary referral center in Auckland.
- Analysis of photopatch test results and subsequent diagnoses.
Main Results:
- Out of 70 patients tested, 6 (10%) showed positive reactions to the photoallergen series.
- Promethazine (4 cases) and benzophenone-3 (2 cases) were the identified photoallergens.
- The most frequent diagnoses included endogenous dermatitis (54%) and allergic contact dermatitis (21%).
Conclusions:
- Photopatch testing is crucial for diagnosing suspected photoallergic contact dermatitis.
- Promethazine and benzophenone-3 were the sole identified photoallergens in this New Zealand cohort.
- Oral promethazine exposure was linked to sensitization, suggesting a systemic photoallergy mechanism.
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