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Systemic therapy and COVID19: Immunotherapy and chemotherapy
Shuchi Gulati1, Ramya Muddasani2, Paulo Gustavo Bergerot3
1Hematology and Oncology, University of Cincinnati Medical Center, Cincinnati, OH.
Urologic Oncology
|January 16, 2021
Summary
Managing cancer treatment during the COVID-19 pandemic is complex. This review focuses on systemic therapies for genitourinary cancers in patients with COVID-19.
Area of Science:
- Oncology
- Infectious Diseases
- Public Health
Background:
- The COVID-19 pandemic presents unique challenges for cancer patient care.
- Decisions involve balancing treatment risks, potential adverse drug effects, and cancer type.
Purpose of the Study:
- To review the management of genitourinary malignancies in patients undergoing systemic therapy while infected with COVID-19.
- To provide guidance amidst evolving pandemic-related treatment complexities.
Main Methods:
- Review of current literature and data from major cancer/COVID-19 registries.
- Analysis of treatment considerations for systemic therapies in genitourinary cancers.
- Focus on patient outcomes and risk stratification.
Main Results:
- Ongoing data collection from registries like TERAVOLT and NCI studies will inform outcomes.
- This review synthesizes existing knowledge to guide clinical decisions.
- Specific challenges in managing genitourinary cancers during COVID-19 are highlighted.
Conclusions:
- Careful consideration of individual patient factors is crucial for managing genitourinary cancers during COVID-19.
- Systemic therapy decisions require balancing oncologic needs with infectious disease risks.
- Further data from large-scale studies are needed to refine treatment protocols.
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