Related Experiment Video
Updated: Nov 21, 2025

Long Term Chronic Pseudomonas aeruginosa Airway Infection in Mice
Published on: March 17, 2014
Ciliated respiratory epithelium encapsulating Pseudomonas brain abscess due to prior trauma
Nihar Kanta Jena1, Justin Khine2, Nadia Khosrodad2
1Internal Medicine, Saint Joseph Mercy Oakland Hospital, Pontiac, Michigan, USA nihar.jena@stjoeshealth.org.
Abstract:
Bacterial brain abscesses are typically spread through a haematogenous route. Open head wounds and neurosurgical interventions are uncommon aetiologies. Ectopic tissue found in the cerebral cortex is usually ascribed almost entirely from carcinomas. Here, we describe a 57-year-old gentleman who, 22 years after a fireworks related traumatic injury to the left orbit, presented with headaches and altered behaviour. Imaging revealed an abscess immediately superior to the orbit, whose bacterial aetiology was identified to be Pseudomonas aeruginosa, encapsulated by ciliated respiratory epithelium. This represents a case in which tissue was displaced during the initial trauma or craniofacial reconstructive surgery from the frontal sinus.
Insights
A rare brain abscess caused by Pseudomonas aeruginosa was found 22 years after a head injury. The abscess was uniquely encapsulated by respiratory tissue, suggesting displacement from the frontal sinus during the initial trauma.
Area of Science:
- Neurology
- Infectious Diseases
- Pathology
Background:
- Bacterial brain abscesses commonly spread hematogenously.
- Uncommon causes include head trauma and surgery.
- Ectopic tissue in the brain is typically from carcinomas.
More Related Videos
09:58A Choroid Plexus Epithelial Cell-based Model of the Human Blood-Cerebrospinal Fluid Barrier to Study Bacterial Infection from the Basolateral Side
Published on: May 6, 2016
07:25Visualization of Pseudomonas aeruginosa within the Sputum of Cystic Fibrosis Patients
Published on: July 16, 2020
Related Concept Videos
Pneumonia I: Introduction
Risk Factors
Various factors influence the likelihood of developing pneumonia. Age plays a crucial role, with infants, children under two, and individuals over 65 at increased risk due to their...
Anatomy of Respiratory System I: Upper Respiratory Tract
Nose and nasal cavity
The nose and nasal cavity represent the main external openings of the respiratory tract....
Pneumonia II: Pathophysiology
Pleura of the Lungs
Cranial and Spinal Meninges
Cranial Meninges
These meningeal layers cover the cranium. The dura mater is the outermost layer of cranial meninges. It is a thick and durable membrane of dense...