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The Interdependence of Blood Pressure and Glucose in Vietnam

Tran Thi Thu Nga1, Christopher Leigh Blizzard2, Luong Ngoc Khue3

  • 1Menzies Institute for Medical Research, University of Tasmania, Private Bag 23, Hobart, TAS, 7000, Australia.

High Blood Pressure & Cardiovascular Prevention : the Official Journal of the Italian Society of Hypertension
|January 16, 2021
PubMed

Insights

This study reveals a feedback loop between systolic blood pressure and blood glucose, influenced by obesity measures like BMI and waist circumference. Interventions targeting diet and physical activity can help manage both conditions.

Area of Science:

  • Cardiovascular Health
  • Metabolic Health
  • Epidemiology

Background:

  • Separate regression models for systolic blood pressure (BP) and blood glucose (BG) overlook shared etiological mechanisms, leading to unreliable inferences.
  • Understanding the inter-dependence of BP and BG is crucial for accurate health assessments.

Purpose of the Study:

  • To investigate the relationship between systolic BP and BG, considering their interdependence.
  • To examine the influence of obesity measures (BMI, waist circumference) and other factors on systolic BP and BG.

Main Methods:

  • A large-scale study in Vietnam (n=14706) using multi-stage stratified cluster sampling.
  • WHO STEPS protocols were employed for data collection in participants aged 25-64.
  • Structural modeling was used to analyze the complex relationships between variables.

Main Results:

  • Direct effects of BG, age, and BMI on systolic BP were observed in both men and women.
  • Systolic BP and waist circumference showed direct effects on BG.
  • Indirect effects of age, cholesterol, physical activity, and smoking on BG and BP were mediated through BMI and waist circumference.
  • Correlated errors between systolic BP and BG estimations indicated a feedback loop.

Conclusions:

  • Statistical evidence supports a feedback loop between systolic BP and BG.
  • Body Mass Index (BMI) and waist circumference (WC) are primary explanatory factors for both systolic BP and BG.
  • Interventions focused on saturated fat intake and physical activity may help reduce overweight/obesity, systolic BP, and BG.
  • Harmful alcohol intake is a target for managing systolic BP.
Abstract

Keywords:
Blood glucoseBlood pressureInter-relationship

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