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Updated: Nov 21, 2025

Engineering Antiviral Agents via Surface Plasmon Resonance
Published on: June 14, 2022
Antiviral Nanostructured Surfaces Reduce the Viability of SARS-CoV-2
Jafar Hasan1, Alyssa Pyke2, Neelima Nair2
1Centre for Biomedical Technologies, Science and Engineering Faculty, Queensland University of Technology, Brisbane, Queensland 4000, Australia.
Abstract:
In this letter, we report the ability of the nanostructured aluminum Al 6063 alloy surfaces to inactivate the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). There was no recoverable viable virus after 6 h of exposure to the nanostructured surface, elucidating a 5-log reduction compared to a flat Al 6063 surface. The nanostructured surfaces were fabricated using wet-etching techniques which generated nanotextured, randomly aligned ridges approximately 23 nm wide on the Al 6063 alloy surfaces. In addition to the excellent mechanical resilience properties previously shown, the etched surfaces have also demonstrated superior corrosion resistance compared to the control surfaces. Such nanostructured surfaces have the potential to be used in healthcare environment such as hospitals and public spaces to reduce the surface transmission of SARS-CoV-2 and combat COVID-19.

