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Updated: Nov 21, 2025

Screening of Axonal Degeneration in Carpal Tunnel Syndrome Using Ultrasonography and Nerve Conduction Studies
Published on: January 11, 2019
Variations ignored in routine wrist MRI reports: prevalence of the median nerve anatomical variations and persistent
Fatih Dag1, Berna Dirim Mete2, Merve Gursoy2
1Department of Radiology, Manisa Turgutlu State Hospital, Manisa, Izmir, Turkey.
Background:
It is vital to know the anatomical variations of the wrist to avoid iatrogenic injuries during carpal tunnel (CT) surgery.
Purpose:
To determine the anatomical variations of the median nerve (MN) and the prevalence of persistent median artery (PMA) on wrist magnetic resonance imaging (MRI).
Material And Methods:
A total of 300 wrists evaluated by MRI during 2013-2015 were retrospectively identified. While branching of the MN distal to the CT is accepted as the normal anatomy, proximal to the tunnel and within the tunnel were considered as variations. The prevalence of PMA was also evaluated. The patients were assigned to groups according to age, gender, and wrist side and compared to determine whether there was any significant difference in terms of these variations. All evaluations were assessed with the shared decision of a musculoskeletal radiologist and a radiology resident.
Results:
Of the 300 wrists, 38 (12.7%) and 34 (11.3%) had a bifid MN proximal to the CT and within the CT, respectively. Only one nerve trifurcation was seen within the CT. The MN exhibited branching distal to the CT in 227 (76%) patients. PMA was observed in 44 (14.7%) patients. Of the 44 PMA cases, 28 (63.6%) also had a coexisting MN variation. There was no significant difference in the prevalence of MN variations and PMA in the subgroups (P > 0.05).
Conclusion:
Nearly one in four patients (24.4%) have MN variations and 14.8% had PMA. Preoperative evaluation of these common anatomical variations with MRI will be protective against postoperative complications of CT surgery.
Insights
Anatomical variations of the median nerve (MN) and persistent median artery (PMA) are common in the wrist. Preoperative MRI can help prevent complications during carpal tunnel (CT) surgery.
Area of Science:
- Anatomy
- Radiology
- Orthopedic Surgery
Background:
- Anatomical variations of the wrist are crucial for preventing iatrogenic injuries during carpal tunnel (CT) surgery.
- Understanding median nerve (MN) and persistent median artery (PMA) variations is vital for surgical safety.
Purpose of the Study:
- To determine the anatomical variations of the median nerve (MN).
- To assess the prevalence of persistent median artery (PMA).
- To evaluate these variations using wrist magnetic resonance imaging (MRI).
Main Methods:
- Retrospective analysis of 300 wrist MRIs from 2013-2015.
- MN variations defined as branching proximal or within the CT.
- Prevalence of PMA and its association with MN variations were evaluated.
Main Results:
- Median nerve (MN) variations were found in 24% of wrists (bifid MN in 12.7% proximal, 11.3% within CT).
- Persistent median artery (PMA) was observed in 14.7% of wrists.
- PMA frequently coexisted with MN variations (63.6% of PMA cases).
Conclusions:
- A significant percentage of individuals exhibit median nerve (MN) variations (24.4%) and persistent median artery (PMA) (14.8%).
- Preoperative MRI assessment for these common anatomical variations can mitigate postoperative complications of carpal tunnel (CT) surgery.
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