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Updated: Nov 21, 2025

A Machine Learning Approach to Design an Efficient Selective Screening of Mild Cognitive Impairment
Published on: January 11, 2020
Sleep, Mild Cognitive Impairment, and Interventions for Sleep Improvement: An Integrative Review
Maral Torossian1, Sarah Marie Fiske1, Cynthia S Jacelon1
1University of Massachusetts Amherst, Amherst, MA, USA.
Abstract:
Sleep disturbance in mild cognitive impairment (MCI) is associated with progression to Alzheimer's disease (AD), more severe AD symptoms, and worse health outcomes. The aim of this review was to examine the relationship between sleep and MCI, and the effectiveness of sleep improvement interventions for older adults with MCI or AD. An integrative review was conducted using four databases, and findings were analyzed using an iterative process. Findings from 24 studies showed that alterations in sleep increased the risk of MCI and that the sleep quality of individuals with MCI or AD was poorer than healthy controls. Changes in brain anatomy were also observed in healthy older adults with sleep disturbances. Examined interventions were shown to be effective in improving sleep. Screening for sleep disturbances in individuals with MCI/AD is crucial to mitigate neurodegenerative or neurobehavioral risks in this population.
Insights
Sleep disturbances worsen mild cognitive impairment (MCI) and increase Alzheimer's disease (AD) risk. Improving sleep quality in older adults with MCI or AD is vital for mitigating cognitive decline and improving health outcomes.
Area of Science:
- Neurology
- Sleep Medicine
- Gerontology
Background:
- Sleep disturbance is a significant risk factor for the progression of mild cognitive impairment (MCI) to Alzheimer's disease (AD).
- Individuals with MCI or AD exhibit poorer sleep quality compared to healthy individuals.
- Sleep disturbances in older adults are linked to anatomical brain changes.
Purpose of the Study:
- To review the relationship between sleep and MCI.
- To evaluate the effectiveness of sleep improvement interventions for individuals with MCI or AD.
Main Methods:
- An integrative review was conducted.
- Data were sourced from four electronic databases.
- Findings were analyzed using an iterative process.
Main Results:
- Alterations in sleep patterns increase the risk of developing MCI.
- Individuals with MCI or AD demonstrate significantly poorer sleep quality than healthy controls.
- Interventions aimed at improving sleep have shown positive effects.
Conclusions:
- Screening for sleep disturbances in individuals with MCI/AD is crucial.
- Addressing sleep issues can help mitigate neurodegenerative and neurobehavioral risks.
- Sleep improvement interventions are effective for older adults with MCI or AD.
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