Related Experiment Video
Updated: Nov 21, 2025

Safety Precautions and Operating Procedures in an ABSL-4 Laboratory: 3. Aerobiology
Published on: October 3, 2016
Historic Firsts: Aeromedical Evacuation and the Transportation Isolation System
Kimberly Reynolds1, Richelle B Bornales2
1Western Reserve Health Education, Warren, OH.
The US Air Force successfully used the Transportation Isolation System operationally for the first time. This system safely transported patients diagnosed with coronavirus disease 2019.
Area of Science:
- Aeromedical Evacuation
- Infectious Disease Control
- Public Health
Background:
- The Transportation Isolation System (TIS) was developed to safely transport patients with highly infectious diseases.
- Previous use of TIS was limited to training and non-operational scenarios.
Purpose of the Study:
- To report the first operational use of the TIS by US Air Force aeromedical evacuation crews.
- To evaluate the effectiveness and safety of TIS in a real-world patient transport scenario.
Main Methods:
- US Air Force aeromedical evacuation crews utilized the TIS for patient transport.
- Patients transported were positive for coronavirus disease 2019 (COVID-19).
Main Results:
- The operational deployment of the TIS was successful.
- Aeromedical evacuation crews demonstrated proficiency in using the system.
- Patients with COVID-19 were safely transported.
Conclusions:
- The TIS is a viable and effective system for the operational aeromedical evacuation of patients with infectious diseases like COVID-19.
- This successful mission validates the TIS for future use in high-consequence infectious disease transport.
Related Concept Videos
Transmission-based Precautions II: Airborne and Protective Environment
Airborne precautions:
Use airborne precautions when treating patients known or suspected to have diseases that spread through the air—for example, tuberculosis or measles. These organisms are present in smaller droplets expelled by an infected person and...
Cardiopulmonary Resuscitation II: ACLS Airway Management
Oxygen Delivering System II: Venturi Mask and Transtracheal Oxygen
Venturi Mask
The Venturi mask, named after the Venturi effect, is designed to deliver precise oxygen concentrations. It consists of a large tube with an oxygen inlet that narrows down, causing a pressure drop that pulls air in through adjustable side ports. The mask is a lightweight,...
Mechanical Ventilation II: Invasive Ventilation
Negative-Pressure Ventilators
Negative-pressure ventilators create a vacuum around the chest or body to draw air into the lungs, simulating breathing. This method does not require an...
Oxygen Delivering System III: Tracheostomy and T-piece
Tracheostomy
A tracheostomy is a surgically created opening (stoma) in the anterior part of the trachea. It is used to establish a patient airway, bypass an upper airway obstruction, simplify the removal of secretions, permit long-term...
Cardiopulmonary Resuscitation V: Advanced Airway Management Techniques

