Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Xanthoderma: case report and differential diagnosis.

K M Stack1, M A Churchwell, R B Skinner

  • 1University of Tennessee/Memphis, Department of Medicine 38163.

Cutis
|February 1, 1988
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Redox-driven mineral and organic associations in Jezero Crater, Mars.

Nature·2025
Same author

Intense alteration on early Mars revealed by high-aluminum rocks at Jezero crater.

Communications earth & environment·2024
Same author

An olivine cumulate outcrop on the floor of Jezero crater, Mars.

Science (New York, N.Y.)·2022
Same author

Aqueously altered igneous rocks sampled on the floor of Jezero crater, Mars.

Science (New York, N.Y.)·2022
Same author

In situ recording of Mars soundscape.

Nature·2022
Same author

Characteristics, Origins, and Biosignature Preservation Potential of Carbonate-Bearing Rocks Within and Outside of Jezero Crater.

Journal of geophysical research. Planets·2021
Same journal

Psoriasis and Obesity: A Clinical Review of the Bidirectional Link and Management Implications.

Cutis·2026
Same journal

Adalimumab in Lichen Planus: A Narrative Review of Treatment and Paradoxical Reactions.

Cutis·2026
Same journal

Metastatic Primary Extramammary Paget Disease: A Case Series.

Cutis·2026
Same journal

A Simple Alternative for Intralesional Cryosurgery of Keloids and Hypertrophic Scars Using a Disposable Infusion Set.

Cutis·2026
Same journal

A Guide to Avoiding Common Procedural Coding Mistakes.

Cutis·2026
Same journal

Dermatology Boards Demystified: Conquer the BASIC, CORE, and APPLIED Exams.

Cutis·2026
See all related articles

Yellow-orange skin discoloration without yellowing of the sclera suggests hypercarotenemia. This case highlights carotenemia from red palm oil ingestion, persisting despite low serum beta-carotene levels.

Area of Science:

  • Dermatology
  • Toxicology
  • Biochemistry

Background:

  • Yellow-orange skin discoloration can stem from various causes, including hyperbilirubinemia, drug effects, and carotenemia.
  • Differentiating these causes is crucial, with scleral icterus presence being a key diagnostic indicator.

Observation:

  • A patient presented with yellow-orange skin pigmentation, but importantly, without scleral icterus.
  • Despite a history of malaria and hepatitis, bilirubin levels were insufficient to cause jaundice.

Findings:

  • The absence of scleral icterus pointed towards non-bilirubin causes.
  • Pigment localization to palms and soles, coupled with a slightly elevated serum beta-carotene, supported hypercarotenemia.
  • This was attributed to significant red palm oil consumption, with tissue carotene levels explaining persistent discoloration despite low serum levels.

Related Experiment Videos

Implications:

  • Scleral examination is vital in diagnosing yellow skin discoloration.
  • Hypercarotenemia can occur from dietary sources like red palm oil.
  • Carotenoid deposition in tissues can cause prolonged skin discoloration independent of current serum levels.