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Isolation and Quantification of Epstein-Barr Virus from the P3HR1 Cell Line
Published on: September 28, 2022
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Epstein-Barr Virus-induced Meningitis-Retention Syndrome
Morika Suzuki1, Genya Watanabe2, Takashi Watari3
1Department of General Internal Medicine, National Hospital Organization Sendai Medical Center, Miyagi, Japan.
European Journal of Case Reports in Internal Medicine
|January 18, 2021
Summary
Meningitis-retention syndrome (MRS), a rare condition causing aseptic meningitis and urinary retention, can be mistaken for a urinary tract infection. Early consideration of MRS is crucial in patients with fever and urinary issues, as bladder symptoms may appear before meningitis signs.
Area of Science:
- Neurology
- Infectious Diseases
- Urology
Background:
- Meningitis-retention syndrome (MRS) is a rare condition characterized by aseptic meningitis and urinary retention.
- MRS is often misdiagnosed as a urinary tract infection due to overlapping symptoms like dysuria.
- Prompt diagnosis and management are essential to prevent complications.
Purpose of the Study:
- To highlight the clinical presentation of Meningitis-retention syndrome (MRS).
- To emphasize the importance of considering MRS in patients presenting with fever and urinary retention.
- To report a case of MRS associated with Epstein-Barr virus.
Main Methods:
- Case report of a 55-year-old male patient.
- Clinical evaluation including assessment of fever, dysuria, and signs of meningeal irritation.
- Diagnostic investigations to identify the underlying cause, including Epstein-Barr virus testing.
Main Results:
- The patient presented with fever and dysuria, initially mimicking a urinary tract infection.
- Meningeal irritation signs developed later in the disease course.
- Epstein-Barr virus was identified as the causative agent for MRS in this case.
Conclusions:
- Meningitis-retention syndrome (MRS) requires consideration in patients with unexplained fever and urinary retention.
- Dysuria can be an early symptom preceding overt meningitis in MRS.
- Epstein-Barr virus is a potential complicating factor in MRS.

