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Cone beam CT based dose calculation in the thorax region
Laura Patricia Kaplan1,2, Ulrik Vindelev Elstrøm1, Ditte Sloth Møller1
1Department of Medical Physics, Aarhus University Hospital, Nørrebrogade 44, 8000 Aarhus, Denmark.
Physics and Imaging in Radiation Oncology
|January 18, 2021
Summary
Accurate radiotherapy dose calculations on Cone Beam CT (CBCT) images are possible for lung cancer patients using a simple stoichiometric calibration. This method achieves approximately 4% accuracy, improving treatment planning and delivery.
Area of Science:
- Medical Physics
- Radiotherapy
- Diagnostic Imaging
Background:
- Cone Beam CT (CBCT) image quality is often limited by scattered radiation, impacting dose calculation accuracy in radiotherapy.
- Accurate dose calculation is crucial for effective lung cancer treatment planning.
Purpose of the Study:
- To investigate the feasibility of stoichiometric calibration for dose calculation on CBCT images in lung cancer patients.
- To assess the accuracy of dose calculations on CBCT compared to CT scans.
Main Methods:
- CBCT calibrations were performed using a thorax phantom to simulate clinical scatter conditions.
- Dose distributions and DVH parameters were compared between CBCT and CT scans in an anthropomorphic phantom and 12 lung cancer patients.
Main Results:
- For phantom studies, 98% of CBCT DVH parameters were within ±3% of CT doses.
- In lung cancer patients, 98% of DVH parameters were within ±4% of CT doses, with a median dose difference of ±2%.
- Tumor minimum dose was underestimated by a median of 1.9% on CBCT, while organs at risk maximum doses were slightly overestimated.
Conclusions:
- Direct dose calculations on lung cancer patient CBCTs are feasible with approximately 4% accuracy.
- A simple stoichiometric calibration method is easily implementable in clinical settings for improved radiotherapy accuracy.
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