Evaluating hematological parameters in women with endometriosis

Area of Science:

• Gynecology
• Hematology
• Immunology

Background:

• Inflammatory factors are implicated in endometriosis pathogenesis.
• Previous studies show inconsistent associations between blood inflammatory markers and endometriosis.

Purpose of the Study:

• To evaluate the relationship between hematological parameters and endometriosis presence and stage.
• To determine if preoperative hematological parameters can aid in endometriosis diagnosis.

Main Methods:

• Retrospective analysis of medical records for endometriosis and control groups.
• Comparison of preoperative hematological parameters between groups.

Main Results:

• Higher neutrophil, white blood cell (WBC) counts, mean platelet volume, neutrophil-to-lymphocyte ratio (NLR), and platelet-to-lymphocyte ratio (PLR) in endometriosis patients.
• Lower hemoglobin, platelet count, and absolute lymphocyte count in endometriosis patients.
• No significant differences in hematological parameters for endometriosis stages III and IV.

Conclusions:

• Endometriosis is associated with inflammatory processes causing hematological changes.
• Preoperative hematological parameters lack diagnostic power for endometriosis.
• These parameters may serve as auxiliary findings in clinical diagnosis.