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Nutritional status improvement in elderly CKD patients: a systematic review
Adelina Mihaescu1,2, Emmad Masood3, Mohammed Zafran3
1V Babes" University of Medicine and Pharmacy, Timișoara, Romania.
International Urology and Nephrology
|January 18, 2021
Summary
Dietary interventions can improve the nutritional status of elderly patients with chronic kidney disease (CKD). This systematic review found positive effects on serum albumin and Subjective Global Assessment (SGA) in frail, malnourished CKD individuals.
Area of Science:
- Gerontology
- Nephrology
- Nutritional Science
Background:
- Elderly patients with chronic kidney disease (CKD) often suffer from poor nutritional status, frailty, and malnutrition.
- Optimizing nutritional status is crucial for managing health outcomes in this vulnerable population.
Purpose of the Study:
- To systematically review primary studies on methods to improve nutritional status in elderly CKD patients.
- To synthesize current evidence on interventions for malnutrition in this demographic.
Main Methods:
- A focused and sensitive search strategy was employed on the PUBMED database for English-language articles.
- Included 19 studies (7 non-randomized controlled trials, 15 randomized controlled trials) with quality and bias assessment.
- Data extraction and analysis were performed by two independent researchers and verified by a third.
Main Results:
- Key outcomes assessed included mortality, Subjective Global Assessment (SGA), serum albumin, total protein, and various amino acids.
- Analysis considered lipids (TAG, HDL, LDL) and other markers like prealbumin and transferrin.
- Despite low trial quality and heterogeneity, a positive effect of dietary interventions was observed.
Conclusions:
- This is the first systematic review focusing on nutritional status in elderly CKD patients.
- Dietary interventions demonstrated a positive impact on nutritional status, notably improving serum albumin and SGA scores.
- Further high-quality, homogeneous trials are needed to confirm these findings.
Keywords:
Chronic kidney diseaseElderly patientsFrailtyMalnutritionNutritional statusSGASerum albuminMore Related Videos
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