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Updated: Nov 21, 2025

Comprehensive Analysis of Procoagulant Platelets Exhibiting Features of Necrosis, Apoptosis and Platelet Activation
Published on: May 23, 2025
Platelets and cancer… the plot doesn't always thicken
Philip Crispin1,2, Elizabeth E Gardiner1
1ACRF Department of Cancer Biology and Therapeutics, The John Curtin School of Medical Research, The Australian National University, Canberra, Australia.
Background:
Platelets have critical roles in preventing blood loss following injury, promoting wound healing, and in fighting infection through innate immune defense strategies.
Key Results:
Deficiencies in platelet number or function either as a result of disease, as a consequence of therapy, or both can lead to dramatic and potentially fatal consequences.
Conclusions And Inferences:
With the advent of new therapeutics targeting pathways within hematological malignant cells that are also important for platelet function, monitoring the state of a patient's haemostasis system is now an important clinical consideration.
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