Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Chemical Agents for Microbial Control01:27

Chemical Agents for Microbial Control

576
Chemicals play important roles in controlling microbial growth by targeting microbial structures and functions as sanitizers, antiseptics, disinfectants, and sterilants.Alcohols are commonly used sanitizers, effectively disrupting lipid membranes, which compromises cell integrity. They are also used as antiseptics and disinfectants due to their rapid action and versatility.Phenols and their derivatives phenolics , known for denaturing proteins and disrupting cell membranes, are particularly...
576
Plant Breeding and Biotechnology01:59

Plant Breeding and Biotechnology

20.6K
Crop cultivation has a long history in human civilization, with records showing the cultivation of cereal plants beginning at around 8000 BC. This early plant breeding was developed primarily to provide a steady supply of food.
20.6K
Hypothesis: Accept or Fail to Reject?01:17

Hypothesis: Accept or Fail to Reject?

29.0K
The outcome of any hypothesis testing leads to rejecting or not rejecting the null hypothesis. This decision is taken based on the analysis of the data, an appropriate test statistic, an appropriate confidence level, the critical values, and P-values. However, when the evidence suggests that the null hypothesis cannot be rejected, is it right to say, 'Accept' the null hypothesis?
There are two ways to indicate that the null hypothesis is not rejected. 'Accept' the null...
29.0K
Plant Hormones01:56

Plant Hormones

26.1K
Plant hormones—or phytohormones—are chemical molecules that modulate one or more physiological processes of a plant. In animals, hormones are often produced in specific glands and circulated via the circulatory system. However, plants lack hormone-producing glands.
26.1K
Hand hygiene01:23

Hand hygiene

5.1K
Asepsis is the practice of preventing or breaking the chain of infection. The nurse employs aseptic techniques to prevent the spread of microorganisms and reduce the risk of diseases. Hand hygiene is the cornerstone of aseptic techniques and is classified into medical and surgical asepsis. Medical asepsis includes hand hygiene and the use of gloves. Surgical asepsis, or the sterile technique, refers to practices that render and keep objects and areas free of microorganisms.
Hand washing...
5.1K
Defenses Against Pathogens and Herbivores02:26

Defenses Against Pathogens and Herbivores

29.0K
Plants present a rich source of nutrients for many organisms, making it a target for herbivores and infectious agents. Plants, though lacking a proper immune system, have developed an array of constitutive and inducible defenses to fend off these attacks.
29.0K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

A Sensitive and Simple Method for Trace Analysis of Pesticide Residues in Plant Guttation Fluids.

Journal of agricultural and food chemistry·2026
Same author

ChroB Site on the GABA RDL Receptor as a Potential Insecticide Target.

Journal of agricultural and food chemistry·2026
Same author

Current Status and Trends of Inducers and Induced-Resistance Strategies in Kiwifruit Preservation.

Comprehensive reviews in food science and food safety·2026
Same author

Diverse radical C-F functionalizations of hexa- to difluoroarenes using boryl radicals as link-and-lose mediators.

Nature chemistry·2026
Same author

Cloning, Expression, and Activity and Structure Characterization of an <i>O</i>-Glycosyltransferase, ZmUGT76B1 from Maize (<i>Zea mays</i> L.).

Journal of agricultural and food chemistry·2026
Same author

Structural insights into the molecular mechanisms of OsFBN5-induced OsSPS3 catalysis.

Nature plants·2026

Related Experiment Video

Updated: Nov 21, 2025

Protocols for Robust Herbicide Resistance Testing in Different Weed Species
10:52

Protocols for Robust Herbicide Resistance Testing in Different Weed Species

Published on: July 2, 2015

14.9K

Where are the new herbicides?

Ren-Yu Qu1, Bo He1, Jing-Fang Yang1

  • 1Key Laboratory of Pesticide & Chemical Biology of Ministry of Education, International Joint Research Center for Intelligent Biosensor Technology and Health, College of Chemistry, Central China Normal University, Wuhan, China.

Pest Management Science
|January 18, 2021
PubMed
Summary
This summary is machine-generated.

Herbicide resistance is a major crop production issue. This review proposes rational design strategies and computational methods to discover novel herbicides and manage resistant weeds, ensuring sustainable agriculture.

Keywords:
glyphosateherbicidemode of actionresistancetarget mutation

More Related Videos

Measuring Rates of Herbicide Metabolism in Dicot Weeds with an Excised Leaf Assay
10:49

Measuring Rates of Herbicide Metabolism in Dicot Weeds with an Excised Leaf Assay

Published on: September 7, 2015

12.3K
Avocado Sample Preparation Using the QuEChERS Method with Ammonium Formate for Pesticide Analysis
05:20

Avocado Sample Preparation Using the QuEChERS Method with Ammonium Formate for Pesticide Analysis

Published on: December 8, 2023

983

Related Experiment Videos

Last Updated: Nov 21, 2025

Protocols for Robust Herbicide Resistance Testing in Different Weed Species
10:52

Protocols for Robust Herbicide Resistance Testing in Different Weed Species

Published on: July 2, 2015

14.9K
Measuring Rates of Herbicide Metabolism in Dicot Weeds with an Excised Leaf Assay
10:49

Measuring Rates of Herbicide Metabolism in Dicot Weeds with an Excised Leaf Assay

Published on: September 7, 2015

12.3K
Avocado Sample Preparation Using the QuEChERS Method with Ammonium Formate for Pesticide Analysis
05:20

Avocado Sample Preparation Using the QuEChERS Method with Ammonium Formate for Pesticide Analysis

Published on: December 8, 2023

983

Area of Science:

  • Agricultural Science
  • Biochemistry
  • Chemical Biology

Background:

  • Herbicide resistance in weeds poses a significant global challenge to crop production.
  • Limited discovery of new herbicides with novel modes of action (MOAs) exacerbates this problem.
  • Developing new herbicides is crucial for effective weed management and maintaining crop yields.

Purpose of the Study:

  • To propose rational design strategies for novel herbicides based on target protein characteristics and inhibitor structures.
  • To introduce a computational method for evaluating the risk of herbicide resistance conferred by target mutations.
  • To enhance the utilization of known herbicide targets and inspire the discovery of herbicides with new targets.

Main Methods:

  • Review and synthesis of existing knowledge on herbicide target proteins and inhibitor structures.
  • Proposal of two distinct strategies for the rational design of new herbicides.
  • Development of a computational risk assessment method for target mutation-conferred resistance.

Main Results:

  • The study outlines specific approaches for designing new herbicides by leveraging inherent target and inhibitor properties.
  • A computational tool is presented to predict and evaluate resistance risks associated with target mutations.
  • The proposed strategies aim to improve the discovery pipeline for herbicides with novel MOAs.

Conclusions:

  • The proposed rational design strategies and computational risk evaluation can accelerate the discovery of new herbicides.
  • These approaches are expected to improve the management of herbicide-resistant weeds.
  • The findings contribute to the sustainable development of herbicides for future agricultural needs.