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Updated: Nov 21, 2025

Modeling Colitis-Associated Cancer with Azoxymethane AOM and Dextran Sulfate Sodium DSS

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Published on: September 11, 2012

Rectal actinomycosis mimicking malignancy.

Akanksha Rajpoot¹, Chiranth Gowda¹, Vidya Monappa²

¹Department of General Surgery, Kasturba Medical College, Manipal Academy of Higher Education, Manipal, India.

Acta Chirurgica Belgica

|January 19, 2021

Summary

This summary is machine-generated.

Abdominal actinomycosis, a rare infection, can mimic colon cancer. Prompt diagnosis and medical management of this Actinomyces infection can prevent extensive surgery.

Keywords:

Sigmoid actinomycosis cancer rectum surgery

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Area of Science:

Gastroenterology
Infectious Diseases
Pathology

Background:

Abdominal actinomycosis is a chronic, suppurative infection caused by Actinomyces species, often affecting the ileocecal region but rarely the left colon.
This infection infiltrates adjacent tissues, making it rarely confined to a single organ and presenting with diverse symptoms, from non-specific signs to acute abdominal conditions.

Observation:

A 56-year-old male presented with rectal bleeding, leading to a colonoscopy revealing an ulcero-proliferative lesion at the recto-sigmoid junction.
The lesion's appearance suggested malignancy, prompting biopsies.

Findings:

Biopsies confirmed the lesion to be abdominal actinomycosis, caused by Actinomyces species.
The patient responded favorably to medical management.

Implications:

This case highlights the importance of considering actinomycosis in the differential diagnosis of colonic lesions, even those mimicking malignancy.
Successful medical treatment avoided the need for major surgical intervention, demonstrating the efficacy of conservative management for abdominal actinomycosis.